The training and testing data is from the HS3D dataset, and excellent accuracy rate is achieved by nucleic acid sequence orthogonal coding and RBF core function, and the cross validation experiment ...

In creative spaces, ‘AI’ has become a dog whistle for human replacement. ‘The Brutalist’ is its first victim. The Brutalist, ...

Pre-mRNA splicing is carried out by the spliceosome which contains more than 100 proteins and 5 U snRNAs. The accuracy and efficiency of the spliceosome are often compromised in many human cancers.

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

The simplest way to install SpliceAI is through pip or conda: ...

As its name suggests, splicing involves snipping out certain sequences in the RNA called introns, with the remaining sequences (exons) reconnected to one another to form the functional molecule.

Because some group II introns can splice auto-catalytically, their splicing ... but have N-terminal mitochondrial targeting sequences (Keren et al., 2009). Similarly to MatR, the four nMATs have a ...

Inverna’s platform originates from the groundbreaking research of Professor Brage Storstein Andresen, an internationally renowned expert in RNA splicing and antisense technology. Inverna aims to ...

Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.