A screen for proteins that interact with β2-syntrophin led to the isolation of MAST205 (microtubule-associated serine/threonine kinase-205 kD) and a newly identified homologue, SAST (syntrophin ...

Resero Therapeutics LLC has divulged serine/threonine-protein kinase PLK1 (STPK13) inhibitors reported to be useful for the treatment of cancer.

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas nonreceptor tyrosine kinases and serine/threonine protein kinases function throughout ...

Deciphera Pharmaceuticals LLC has patented new serine/threonine-protein kinase B-raf (BRAF) and/or RAF proto-oncogene serine/threonine-protein kinase (RAF1; c-Raf) inhibitors reported to be useful for ...

Acrivon Therapeutics, Inc. (ACRV – Research Report) received a Buy rating and price target from Cantor Fitzgerald analyst Li Watsek today.

Ivermectin, on the other hand, reduces the production of STAT3 and IL-6 by inhibiting p21 activated kinase (PAK1), an oncogenic serine threonine kinase. The efficacy of this medicine was proven in ...

uhnresearch.ca Objectives Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo mechanism of mTOR ...

Upstream reactivation of associated proteins such as Aurora Kinase A (AURKA), a serine/threonine kinase essentially involved in mitosis and DNA repair, has been shown to facilitate effector activation ...

Men have two birth control options: condoms and vasectomies. Why has it taken so long to develop more contraceptives?

Chronic liver damage in BMP-9-deficient mice or in mice adenovirally overexpressing the selective BMP-9 antagonist activin-like kinase 1-Fc resulted in reduced deposition of collagen and subsequent ...

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