The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.
just over 15% of participants with gout for less than 10 years had tophaceous disease. Creatinine clearance was the major factor independently associated with early presentation with tophi.
Objective To investigate the effect of intensive lowering of serum uric acid (SUA) levels by pegloticase on the resolution of tophi in patients with refractory gout. Methods Descriptive study in ...
Gout flares among adults in the United States are significantly underreported to healthcare providers, with nearly 72% of flares either not reported or pretreated/prevented by patients, according to ...
This condition has now been observed to present all the clinical manifestations of gout, including hyperuricemia, urinary tract crystals and calculi, renal failure, arthritis and tophi.