CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

CRISPR-Cas9 is one of the biggest discoveries of the 21st century. Since it was developed in 2012, this gene-editing tool has revolutionized biology research, making it easier to study disease and ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But ...

never ring quite as true as when you glance down at your fingernails and notice that all of the sudden they’re tinged yellow. Eek! But don't freak out just yet. We caught up with two board ...

However, the contribution of additional SLC superfamily members to ferroptosis remains poorly understood. Here, we use a targeted CRISPR-Cas9 screen of the SLC superfamily to identify SLC25A1 as a ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

A warning will always end up somewhere on the matrix, with only one of 16 squares on it dedicated to red. What it means: Yellow warnings are the lowest on the scale, but they are still significant ...

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Dec. 18, 2024 — Artificial light can wake sleeping fish and attract predators, changing nighttime coral reef communities, according to new research using novel ...