Eculizumab biosimilar Elizaria demonstrates long-term safety and efficacy comparable with the reference product Soliris in ...

In the ≥18-year-old group, the signals were strong for extravascular hemolysis, hemoglobinuria, decreased total complement activity, increased total complement activity, meningococcal sepsis, and ...

The diagnosis of hemolytic anemia was established mainly by the clinical observation of either a fall in circulating hemoglobin levels or a loss of transfused blood in excess of 1 per cent per day.

Department of Global Health School of Public Health Wuhan University, Wuhan 430071, China Global Health Institute School of Public Health Wuhan University, Wuhan 430071, China ...

A novel drug combination, improvements in quality of life, and breakthrough hemolysis control are among the clinical highlights in paroxysmal nocturnal hemoglobinuria (PNH) presented at the 2024 ...

In PNH patients experiencing substantial extravascular hemolysis while receiving ravulizumab, zaltenibart monotherapy resulted in sustained clinically meaningful improvements in both hemoglobin ...

SAN DIEGO—Breakthrough hemolysis occurred at a low rate with add-on danicopan therapy in patients with paroxysmal nocturnal hemoglobinuria (PNH) and clinically significant extravascular hemolysis ...

(Getty Images) In testing, a machine learning algorithm achieved 87% sensitivity, 75% specificity, and an area under the curve of 0.80. Patients who tested positive for extravascular hemolysis ...

Breakdown of red blood cells by electroporation has been described in experimental studies, so it stands to reason that at an ablative electrical field intensity and total delivered dose, hemolysis ...