Pharmacological inhibition of AURKA phosphorylation also resulted in reduced liver fibrosis in vivo. Conclusion: In conclusion, AURKA may promote HSC activation and liver fibrosis through the ...

“That makes things a little harder for law enforcement.” “We have a level of polarization in the U.S. that’s an important factor,” he said. “The online environment has algorithms ...

A reduction in oxidation phosphorylation is considered to be a hallmark of pro-inflammatory macrophage polarization. This study shows that respiratory inhibition is not required for macrophage ...

Background Aberrant Wnt pathway activation is a key driver of colorectal cancer (CRC) and is essential to sustain tumour growth and progression. Although the downstream protein-coding target genes of ...

This polarization was amplified by fewer theatrical releases in 2024, which he attributes partially to production delays from COVID-19 and increased selectivity about theatrical projects.

Persuading the Republicans, Democrats and independents in his pews to stay and pray with one another is getting more complicated, so the Rev. Jonathan Hall has lots of strategies for his ...

Laboratory of Theoretical and Computational Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China ...

The study was published in the journal JCI Insight. Macrophages are immune cells that reside in and protect the lungs and are also recruited to the lungs in high numbers during injury or disease ...

Recent studies suggest that these effects are partly mediated through the regulation of macrophage polarization, wherein macrophages differentiate into pro-inflammatory M1 or anti-inflammatory M2 ...

Given heightened tensions over politics and movements such as #MeToo and Black Lives Matter, polarization in the workplace is worse than ever before. Fostering passionate debate and preserving ...