For the multifaceted and complex diseases, multi-omics could define groups of patients with distinct endotypes exhibiting heterogeneous treatment responses due to their particular underlying molecular ...

myriophylla (AME) was dissolved in a vehicle which composed of propylene glycol, Tween 80, and distilled water (4:1:4). The vehicle, AME (1%, 7.5%, and 15% w/v) or indomethacin (0.5 mg/ear in 20 µl of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Thermogenic fat, including brown and beige fat ...

Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around ...

Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Qingdao 266237, P. R. China ...

Scientists investigating Alzheimer’s disease have made a key breakthrough, identifying a vital cellular mechanism driving the most common cause of dementia. The research from the City University ...

Third, it is plausible that acetaminophen may have differential effects in antihypertensive-treated versus untreated patients. The exact mechanism through which acetaminophen may increase BP is ...

Unraveling these mechanisms would offer therapeutic options to ameliorate or perhaps even cure disorders that are now leading causes of mortality. In this millenium, we will be required to answer ...

To this end, the innate RNA interference (RNAi) mechanism can be employed to develop front line therapies against the virus. This approach allows specific binding and silencing of therapeutic targets ...