Alpha- vs. Beta-Thalassemia: Types, Symptoms, and More - Healthline
2024年2月1日 · Learn what distinguishes alpha- from beta-thalassemia and how they differ in their symptoms and outlook.
Alpha Thalassemia - Johns Hopkins Medicine
Alpha thalassemia occurs when 1 or more of the 4 alpha-globin genes that make up part of the hemoglobin molecule are missing or damaged. There are 4 types of alpha thalassemia: Alpha thalassemia silent carrier. One gene is missing or damaged, and the other 3 are normal. Blood tests are often normal. Your red blood cells may be smaller than normal.
Alpha- and Beta-thalassemia: Rapid Evidence Review - AAFP
Ineffective production of alpha- or beta-globin chains may result in ineffective erythropoiesis, premature red blood cell destruction, and anemia. Chronic, severe anemia in patients with...
Thalassemia: Types, Traits, Symptoms & Treatment - Cleveland Clinic
2022年6月3日 · There are two types of thalassemia — alpha thalassemia and beta thalassemia — named after defects in these chains. Alpha thalassemia. You inherit four genes, two from each parent, that make alpha globin protein chains. When one or more genes are defective, you develop alpha thalassemia.
Thalassemia - Symptoms and causes - Mayo Clinic
2021年11月17日 · Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. The mutations associated with thalassemia are passed from parents to children. Hemoglobin molecules are made of chains called alpha and beta chains that can be affected by mutations.
About Thalassemia | Thalassemia | CDC - Centers for Disease …
When we talk about different "types" of thalassemia, we might be talking about one of two things: the specific part of hemoglobin that is affected (usually either "alpha" or "beta"), or the severity of thalassemia, which is noted by words like trait, carrier, intermedia, or major.
What is Thalassemia? | CAF
In addition to the Alpha and Beta Thalassemias, there are other related disorders that occur when the gene for alpha or Beta Thalassemia combines with an abnormal or mutant gene. E Beta Thalassemia. Hemoglobin E is one of the most common abnormal hemoglobins. It is usually found in people of Southeast Asian ancestry, such as Cambodians ...
Alpha Thalassemia and Beta Thalassemia - HealthyChildren.org
2024年3月21日 · Alpha and Beta thalassemias are common inherited forms of anemia that affect millions of people around the world. Most people have a mild form of thalassemia without any problems, while others have more severe but rare forms that need medical help.
Thalassemia - StatPearls - NCBI Bookshelf - National Center for ...
2023年8月8日 · Thalassemias are a heterogeneous grouping of genetic disorders that result from a decreased synthesis of alpha or beta chains of hemoglobin (Hb). Hemoglobin serves as the oxygen-carrying component of the red blood cells. It consists of two proteins, an alpha, and a …
Thalassemia - Wikipedia
Alpha thalassemia is caused by deficient production of the alpha globin component of hemoglobin, while beta thalassemia is a deficiency in the beta globin component. [7] The severity of alpha and beta thalassemia depends on how many of the four genes for alpha globin or two genes for beta globin are faulty. [2]