Lysosome - Wikipedia
The lysosomal membrane protects the cytosol, and therefore the rest of the cell, from the degradative enzymes within the lysosome. The cell is additionally protected from any lysosomal acid hydrolases that drain into the cytosol, as these enzymes are pH-sensitive and do not function well or at all in the alkaline environment of the cytosol.
Lysosome - Definition, Function & Structure - Biology Dictionary
2017年4月28日 — Lysosomes are specialized vesicles within cells that digest large molecules through the use of hydrolytic enzymes. Vesicles are small spheres of fluid surrounded by a lipid bilayer membrane, and they have roles in transporting molecules within the cell.
Lysosomes as dynamic regulators of cell and organismal homeostasis - Nature
2019年11月25日 — The acidic pH of the lysosomal lumen is maintained by a vacuolar ATPase (v-ATPase) embedded in the limiting membrane. In addition, the lysosomal membrane comprises highly glycosylated...
Lysosome | Description, Formation, & Function | Britannica
2024年10月30日 — Lysosome, subcellular organelle that is found in nearly all types of eukaryotic cells and that is responsible for the digestion of macromolecules, old cell parts, and microorganisms. Each lysosome is surrounded by a membrane that maintains an acidic environment marked by the presence of hydrolytic enzymes.
The lysosome as a cellular centre for signalling, metabolism …
2019年1月2日 — The lysosome responds dynamically to many cellular processes. Lysosomal membrane proteins determine the contents of the lysosome.
Lysosomes - The Cell - NCBI Bookshelf - National Center for ...
Lysosomes are membrane-enclosed organelles that contain an array of enzymes capable of breaking down all types of biological polymers—proteins, nucleic acids, carbohydrates, and lipids. Lysosomes function as the digestive system of the cell, serving both to degrade material taken up from outside the cell and to digest obsolete components of ...
Lysosomes as coordinators of cellular catabolism, metabolic
2023年11月24日 — Several lysosomal membrane proteins and peripherally associated proteins cooperate to sense overall cellular nutrient status by sampling both the lysosomal lumenal content and the cytoplasmic...
The lysosomal membrane—export of metabolites and beyond
2020年10月17日 — Lysosomes are degradative organelles in eukaryotic cells mediating the hydrolytic catabolism of various macromolecules to small basic building blocks. These low-molecular-weight metabolites are transported across the lysosomal membrane and reused in the cytoplasm and other organelles for biosynthetic pathways.
Lysosomes: Current Biology - Cell Press
2015年4月20日 — Lysosomes are membrane-bound organelles that are found in animal cells and contain over 50 different acid hydrolases. These dynamic organelles function at the end of the endocytic, autophagic and phagocytic pathways, with lysosomal acid hydrolases being used to break down a wide variety of macromolecules delivered through these pathways.
Lysosomal Physiology - PMC
The lysosomal membrane potential (Δψ) is cytosolic-side negative, with Δψ ranging from −20 to −40 mV. The products of lysosomal degradation, such as amino acids (AAs), sugars, and lipids, are transported out of the lysosome via specific exporters.