Metabolic bone disorders result from abnormally low levels of calcium and phosphorus, minerals that support the growth and strength of the bones. Symptoms include aching bones and frequent fractures in older adults, or delayed bone growth in children.

Metabolic bone diseases are a group of conditions that affect bone mass, bone turnover and bone growth. Some metabolic bone diseases are more common than others, but all of them affect the health of your bones. With proper diagnosis and treatment, you can live an active and fulfilling life.

Metabolic bone disease, any of several diseases that cause various abnormalities or deformities of bone. Examples of metabolic bone diseases include osteoporosis, rickets, osteomalacia, osteogenesis imperfecta, marble bone disease (osteopetrosis), Paget disease of bone, and fibrous dysplasia.

Metabolic bone disease (MBD) is an umbrella term that encompasses a broad spectrum of clinically different diseases that share the common finding of an aberrant bone chemical milieu leading to a defective skeleton and bone abnormalities.

Metabolic bone disease is a loose term that encompasses diseases of bone in which abnormal bone remodelling results in a reduced volume of mineralized bone and/or abnormal bone architecture. These processes in turn give rise to bone pain and usually an …

Metabolic bone diseases are a heterogenous group of conditions that all result in aberrant bone mineral homeostasis with resulting skeletal disease. The underlying causes are variable, ranging from nutritional deficiencies to pathogenic variants in skeletal genes.

2024年8月7日 · There are commonly changes in circulating calcium, phosphate and vitamin D derivatives. Unfortunately there does not appear to be a strict definition of what comprises a metabolic bone disease. When rare genetic entities are included, there results a very long list of conditions under this somewhat woolly umbrella term 1,2.

2023年1月11日 · Metabolic bone disease is a broad term that describes disorders that affect bone strength due to bone mineral, vitamin D, mass, or structural alterations. Clinically, this might result in the weakening of bones, bone pain, and loss of bone height. What Is Bone Actually Made Of? Bone is mainly composed of organic and inorganic components.

This review compiles information on the most common metabolic bone diseases (osteoporosis, primary hyperparathyroidism, osteomalacia, and fluorosis disease) seen in the global population, including their symptoms, mechanisms, and causes, as well as discussing their prevention and the development of new drugs for treatment.

What are Metabolic Bone Diseases? The bones in our bodies are living tissue, so bone metabolism is affected by nutrition, exercise, medical illness and medications, as well as hormones including parathyroid hormone, vitamin D, estrogen, and testosterone.