Pulmonary surfactant - Wikipedia
Surfactant immune function is primarily attributed to two proteins: SP-A and SP-D. These proteins can bind to sugars on the surface of pathogens and thereby opsonize them for uptake by phagocytes. It also regulates inflammatory responses and interacts with the …
The Role of Surfactant in Lung Disease and Host Defense against ...
Pulmonary surfactant is essential for life as it lines the alveoli to lower surface tension, thereby preventing atelectasis during breathing. Surfactant is enriched with a relatively unique phospholipid, termed dipalmitoylphosphatidylcholine, and four surfactant-associated proteins, SP-A, SP-B, SP-C, and SP-D.
Lung surfactant: Function and composition in the context of ... - PubMed
Lung surfactant is a complex with a unique phospholipid and protein composition. Its specific function is to reduce surface tension at the pulmonary air-liquid interface. The underlying Young-Laplace equation, applying to the surface of any geometrical structure, …
Surfactant - StatPearls - NCBI Bookshelf - National Center for ...
2023年6月12日 · Pulmonary surfactant is a lipoprotein complex that lines the alveoli and decreases the surface tension to prevent lung atelectasis. Surfactant deficiency is a documented cause of neonatal respiratory distress syndrome (NRDS), a significant cause of morbidity and mortality in premature infants.
The Biophysical Function of Pulmonary Surfactant - PMC
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two key aspects of this function: that the surfactant film forms rapidly; and that when compressed by the shrinking alveolar area during exhalation, the film reduces surface tension to very low values.
Pulmonary Surfactant - an overview | ScienceDirect Topics
Physiologically, pulmonary surfactant functions to increase pulmonary compliance, prevent atelectasis (collapse of the lung) at the end of expiration and facilitate recruitment of collapsed airways during inhalation.
Surfactant and its role in the pathobiology of pulmonary infection
Pulmonary surfactant is a complex surface-active substance comprised of key phospholipids and proteins that has many essential functions. Surfactant’s unique composition is integrally related to its surface-active properties, its critical role in host defense, and emerging immunomodulatory activities ascribed to surfactant lipids.
The biophysical function of pulmonary surfactant - Cell Press
2024年6月18日 · This review focuses on the major biophysical processes by which endogenous pulmonary surfactant achieves its function and the mechanisms involved in those processes. Vesicles of pulmonary surfactant adsorb rapidly from the alveolar liquid to form the interfacial film.
What Is a Pulmonary Surfactant? - iCliniq
2023年6月12日 · Pulmonary surfactant decreases the surface tension of the lungs by increasing compliance by making lung inflation easier and decreasing the work process of breathing. It also decreases the pressure difference.
Pulmonary Surfactant: Function & Role - StudySmarter
pulmonary surfactant - Key takeaways. Definition: Pulmonary surfactant is a lipid and protein mixture secreted by alveolar cells, reducing surface tension to aid breathing. Function: It reduces alveolar surface tension, supports stability, facilitates gas exchange, and aids in immune defense.