Osteocyte | Definition, Function, Location, & Facts | Britannica
Osteocyte, a cell that lies within the substance of fully formed bone. The osteocyte is capable of bone deposition and resorption. It also is involved in bone remodeling by transmitting signals to other osteocytes in response to deformations of bone caused by muscular activity.
Osteocyte - Wikipedia
An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2] Osteocytes do not divide and have an average half life of 25 years.
Histology, Osteocytes - StatPearls - NCBI Bookshelf
2023年5月1日 · Osteocytes, the prevalent and advanced-most bone cells, and osteocyte-derived proteins (i.e., sclerostin) lead to the development of newer strategies to treat various orthopedic conditions. Researchers recognize that sclerostin as a vital molecule governing bone health.
Osteocyte - Definition and Examples - Biology Online Dictionary
2022年7月29日 · Osteoblasts that have become surrounded by the bone matrix are referred to as osteocytes. As osteocytes may have appeared ‘entombed’ in the mineralized matrix, they are not dead cells. Osteocytes have some interesting features. For instance, osteocytes can live long, depending on the skeletal age.
Osteocyte - an overview | ScienceDirect Topics
Once an osteoblast has enclosed itself within bone matrix, it is called an osteocyte. Long-lived, metabolically active osteocytes are connected to each other by many long, slender filopodia that run through narrow channels in the matrix ( Fig. 32.4D–E ).
A Review of Osteocyte Function and the Emerging Importance …
Osteocytes orchestrate bone resorption and bone deposition by controlling osteoclast and osteoblast activity. Osteocytes release RANKL (receptor activator of nuclear factor kappa-β ligand) to induce osteoclast differentiation, as well as OPG (osteoprotegerin) to downregulate osteoclastogenesis.
Osteocytes: Master Orchestrators of Bone - PMC
Osteocytes are former osteoblasts that become surrounded by unmineralized matrix (osteoid) during bone formation; they make up 90–95% of the adult bone cell population. The complex phenotypic transition from osteoblast to osteocyte has been reviewed recently [1].
The Osteocyte: From “Prisoner” to “Orchestrator” - PMC
Osteocytes are the most abundant bone cells, entrapped inside the mineralized bone matrix.
The osteocyte: A multifunctional cell within the bone
2020年1月1日 · This review highlights and updates the current state of knowledge of the osteocyte and focuses on its roles in bone remodeling and mineral homeostasis, and also reviews its recently discovered endocrine function.
Osteocyte - an overview | ScienceDirect Topics
Osteocytes are approximately 90%–95% of all bone cells, while osteoclasts and osteoblasts fewer than 10%. The osteocyte is defined as a cell surrounded by mineralized matrix. Osteocyte apoptosis is linked to bone remodeling as a result of what …