2011年2月11日 · Knizocytes are triconcave RBCs with a “ridge,” a “bridge” separating the three concavities (in scanning electron micrograph), or a strip of hemoglobin crossing the clear central area (in standard staining).

The term knizocyte describes a specific shape form of erythrocytes that deviates from the standard form. These cells have two concavities instead of the one seen with normal erythrocytes. Like normal red blood cells, knizocytes show a clear central area, …

Synonyms: Cup cell, Knizocyte, Slit cell Erythrocytes with a mouth- or slit-shaped central pale part, making them resemble coffee beans or kissing lips. This shape abnormality arises from a change in the cell's membrane or ion homeostasis due to lipid disorders, hereditary defects, low pH or cationic medication.

Affiliation 1 Service d'Hématologie biologique, Centre Hospitalier Universitaire, Nancy, France. [email protected]

2016年6月12日 · Knizocyte. Blood film and scanning micrograph. A cell with three concavities. The prefix knizo- is derived from ruffle or ridge, the latter separating the concavities.

The characteristic features of fatigue damage in RBC membranes include pronounced shape changes from a disk shape into elliptocyte, stomatocyte, or knizocyte-like shapes, as well as the development of single to multiple thorny projections on cell membranes (SI Appendix, Fig. S2E).

Knizocytes are triconcave RBCs with a ‘‘ridge,’’ a ‘‘bridge’’ separating the three concavities (in scanning electron micrograph), or a strip of hemoglobin crossing the clear central area (in standard staining).

Stomatocyte " and knizocyte. Fig. 7. Knizocytes are triconcave erythrocytes. They can be seen in hereditary or other spherocytoses. They can also be produced by experimental manipulations or occur as artifacts of desiccation during preparation of …

One set of agents, including anionic amphipaths, high salt, high pH, ATP depletion, cholesterol enrichment, and proximity to a glass surface, induces a series of crenated shapes, called echinocytes, characterized by convex rounded protrusions or spicules.

Among red cell morphologic parameters evaluated, knizocytes, rather than ovalocytic morphology, proved the strongest predictor of SAO status (odds ratio [OR] = 19.2; 95% confidence interval [95% CI] = 14.6–25.3; P = <.0001).