2018年4月15日 · Patients requiring >45% reduction in LDL-C may be started at 40 mg once daily. Range: 10 to 80 mg once daily. Adjustments should be made at intervals of 2-4 weeks.

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Table 5. Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) 62 61 60 80mg ($9 gen, $ 236. br) 59 58 56 20 mg 54 ($196) 52

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet]. From ACC / AHA, 2018. 199 Dosages shown are total daily dosages; exceptions are noted.

for patients that may need to be transitioned away from simvastatin (Zocor) 80 mg or Vytorin 10/80 mg. The following table is provided to help approximate the LDL lowering of various statin products.

Calculation of equivalent doses of statins : Active agent 1: Active agent 2: Drug name : Dose in mg: Equivalant dose in mg ...

2017年12月15日 · Doses of Statins (mg) Required to Achieve Various Reductions in LDL-C From Baseline. * 2013 ACC/AHA guidelines: high-intensity statin lowers cholesterol by >50%, moderate-intensity statin lowers cholesterol by 30-50%, low …

Initial dose of 10mg with history of significant renal impairment. Max dose of 10mg for patients with CrCl <30 mL/min, not on hemodialysis. Initial dose of 5mg in severe renal insuficiency. *For all statins, check liver function tests at baseline and when clinically indicated.

Moderate-intensity statins typically reduce LDL-C by 30–49%, lowering ASCVD risk by approximately one-third. High-intensity statins achieve greater reductions (>50%), translating to a risk reduction of about 50%.

Always consult with a healthcare professional for accurate dosing recommendations.