Strychnine poisoning is poisoning induced by strychnine. It can be fatal to humans and other animals and can occur by inhalation, swallowing or absorption through eyes or mouth.

2024年9月6日 · Strychnine poisoning can cause extremely serious negative health effects, including death. Strychnine is a white, odorless, bitter crystalline powder. It can be taken by mouth, breathed in, or mixed in a solution and given intravenously (injected directly into a vein).

Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. [8] While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart [ 9 ] and bowel stimulant [ 10 ] and ...

2023年8月7日 · Strychnine poisoning occurs via accidental or intentional ingestion of compounds containing the chemical. Typically, strychnine is used intentionally for suicidal or homicidal means. Strychnine poisoning may also occur unintentionally by ingesting the Chinese or Cambodian herbal remedies, Miqianzi and slang nut, respectively.

2012年9月22日 · Patients poisoned with strychnine will have a rapid onset of symptoms, typically within an hour of exposure. Diffuse, involuntary muscle contractions are the hallmark of toxicity. Episodes of muscle contractions are classically caused by innocuous stimuli, such as turning on a light or loud sounds.

2023年7月7日 · Strychnine toxicity is a serious medical emergency that requires immediate medical attention. Recognizing the symptoms of strychnine poisoning and providing timely treatment is crucial for minimizing complications and improving outcomes.

Strychnine poisoning can cause extremely serious adverse health effects, including death. Where strychnine is found and how it is used • The primary natural source of strychnine is the plant Strychnos nux vomica.

2015年9月1日 · Strychnine is still used as a rat poison, although it’s falling out of popularity, both because it’s considered inhumane even for rats, and because it’s often eaten by other animals—including...

Strychnine is highly acutely toxic by the oral and ocular and presumably by the inhalation routes of exposure. In addition, numerous incidents have been reported. Additional information including poisoning incident data and end-use product acute toxicity are required for EPA to reach a decision on eligibility for residential uses.

Strychnine is absorbed rapidly after ingestion or nasal inhalation and distributed rapidly into the tissues. It has low plasma protein binding and a large volume of distribution (Vd estimated at 13 L/kg in one case report).