Anterior Horn Cell Disease - an overview | ScienceDirect Topics
The most common anterior horn cell disease worldwide is poliomyelitis but effective vaccination programmes have made this condition rare in the UK, where motor neurone disease is more common. Table 1 .
Motor Neuron Disease - StatPearls - NCBI Bookshelf
2020年10月11日 · Motor neuron disease (MND) is said to be a progressive neurological disorder that presents with both lower motor neurons (anterior horn cells that project from the brainstem and the spinal cord to the muscle) and upper motor neuron signs (neurons that project to the brainstem and spinal cord from higher cortical centers).[1]
Motor Neuron Disease (Amyotrophic Lateral Sclerosis)
Amyotrophic lateral sclerosis is an insidiously developing, adult-onset, progressive anterior horn cell degeneration with associated degeneration of descending motor pathways. It has been recognized as an important clinical syndrome since the middle of the 19th century.
Anterior Horn Cell Disease - an overview | ScienceDirect Topics
The clinical hallmarks of anterior horn cell disease are the lower motor neuron signs of weakness, wasting (atrophy), and fasciculations. These signs may be seen alone or in combination with upper motor neuron signs (hyper-reflexia, upgoing toes) in the case of ALS.
Anterior Horn Cell - an overview | ScienceDirect Topics
The anterior horn cell is a motor neuron that projects from the anterior portion of the grey matter in the spinal cord to the skeletal muscle. The degeneration of these cells causes denervation of the muscles and weakness, the hallmark feature of this disease.
Differentiating lower motor neuron syndromes | Journal of …
Lower motor neuron (LMN) syndromes are clinically characterised by muscle atrophy, weakness and hyporeflexia without sensory involvement. They may arise from disease processes affecting the anterior horn cell or the motor axon and/or its surrounding myelin.
Peripheral Nerve Disorders and Anterior Horn Cell Diseases
2024年11月29日 · Anterior horn cell (also known as motor neuron) diseases affect the most proximal portion of the motor unit and are primarily inherited or infectious. The spinal muscular atrophies are the major inherited disorders of the anterior horn cell.
Spinal Muscular Atrophy - GeneReviews® - NCBI Bookshelf
2000年2月24日 · Spinal muscular atrophy (SMA) is characterized by muscle weakness and atrophy resulting from progressive degeneration and irreversible loss of the anterior horn cells in the spinal cord (i.e., lower motor neurons) and the brain stem nuclei.
Anterior Horn Cell Diseases - SpringerLink
Disorders of the anterior horn cell (AHC) can either be acquired or inherited. Acquired diseases are mainly of viral origin and most of these run an acute course. They include poliomyelitis and similar diseases due to enteroviruses other than poliovirus.
Anterior Horn Cell Diseases - SpringerLink
2020年6月9日 · Disorders of the anterior horn cell (AHC), also known as motor neuron diseases, may have acquired or inherited origins. Acquired diseases are mainly of viral origin, and most of these have an acute presentation. They include poliomyelitis and …