11.10: Antisense RNA - Biology LibreTexts
2022年5月14日 · Transgenic tomatoes have been constructed that carry in their genome an artificial gene (DNA) that is transcribed into an antisense RNA complementary to the mRNA for an enzyme involved in ethylene production.
Antisense RNA: the new favorite in genetic research - PMC
Antisense RNA molecule represents a unique type of DNA transcript that comprises 19–23 nucleotides and is complementary to mRNA. Antisense RNAs play the crucial role in regulating gene expression at multiple levels, such as at replication, transcription, and translation.
Antisense - National Human Genome Research Institute
5 天之前 · Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for producing messenger RNA (mRNA), which directs the synthesis of a protein.
Antisense RNA Design, Delivery, and Analysis - NCBI Bookshelf
1. Introduction to Synthetic Antisense Oligonucleotides and siRNA; 2. Oligonucleotide Synthesis; 3. Synthetic Oligonucleotide Analogues in Antisense and siRNA; 4. RNase H Active Gapmer Chemistry for Use as Drugs; 5. siRNA Chemistry for Use as Drugs; 6. Immune Responses to Nucleic Acids; 7. Conjugates and Delivery; 8. Further Developments in ...
Antisense RNA: Function and Fate of Duplex RNA in Cells of …
In polyomavirus-infected mouse NIH 3T3 fibroblasts, natural antisense RNA to viral early-strand transcripts is produced at late times in infection (Fig. 1). This antisense RNA is responsible for the downregulation of viral early-gene expression late in infection.
Antisense RNA Therapeutics: A Brief Overview - Antisense RNA …
2022年2月25日 · With the irruption of the mRNA vaccines against SARS-CoV-2 special attention has been given to this type of therapies but other types of nucleic acid therapeutics, coined antisense oligonucleotides (AONs), have been studied for many years.
Antisense RNA - an overview | ScienceDirect Topics
Antisense RNA is a single-stranded RNA that is complementary to, and hybridizes with, a protein-coding messenger RNA (mRNA), thereby blocking its translation. By interfering with mRNA translation and the post-transport processing of related genes, antisense RNA results in the down-regulation of the target gene.
Recent insights into the functions and mechanisms of antisense RNA ...
2024年1月9日 · These antisense RNAs play a crucial role in regulating gene expression at various stages, including replication, transcription, and translation. Additionally, artificial antisense RNAs have demonstrated their ability to effectively modulate gene expression in host cells.
Antisense RNA: the new favorite in genetic research - PubMed
Antisense RNA molecule represents a unique type of DNA transcript that comprises 19-23 nucleotides and is complementary to mRNA. Antisense RNAs play the crucial role in regulating gene expression at multiple levels, such as at replication, transcription, and translation.
Gene regulation by antisense transcription - Nature
2013年11月12日 · Antisense transcripts can regulate the expression of their target genes at one or multiple steps of the gene expression process, from transcription and translation to RNA degradation....
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