2019年1月31日 · With current antithrombotic therapies, bleeding remains a concern and limits our ability to provide the most effective therapy to patients with or at risk of thrombosis. Recent advances in our understanding of the contribution of thrombin generation to arterial thrombosis and the role of platelets in venous thrombosis have prompted new ...

An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi). [1][2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus).

2023年7月17日 · The decision to hold, bridge, or resume anticoagulant therapy for a patient is based on the patient's clinical condition, and established guidelines. This article focuses on recommendations formulated to assist providers in developing periprocedural antithrombotic management plans.

2020年8月11日 · In patients with atherosclerotic vascular disease, antithrombotic medication has been applied since the late 1950s of the past century. Traditionally, platelets were regarded key players in atherothrombosis; hence much focus has …

Antithrombotic therapy has reduced the risk of blood clots in leg veins (also known as deep-vein thrombosis or DVT), a condition that can lead to death from pulmonary embolism (a clot that blocks an artery to the lungs) by more than 70 percent.

Anticoagulants are medicines that increase the time it takes for blood to clot. They are commonly called blood thinners. There are several different types of anticoagulant. Each type works at a different level on the blood coagulation pathway. Some can be given by mouth; others can only be given by injection. What are anticoagulants used for?

2024年2月23日 · Antithrombotic therapy aims to prevent blood clots and the serious damage they can cause. Types include anticoagulants like heparin, antiplatelets like aspirin, and emergency thrombolytics.

Abraham et al. Risk of Lower and Upper Gastrointestinal Bleeding, Transfusions, and Hospitalizations With Complex Antithrombotic Therapy in Elderly Patients. Circulation 2013;128:1869(Combining antithrombotic drugs increases UGI bleed risk by …

Antithrombotic drugs, including anticoagulants, antiplatelets, and fibrinolytic agents, are the cornerstone of prevention and treatment of atherosclerosis (i.e., MI and stroke), venous thromboembolic disorders, and the complications of atrial fibrillation (AF) [79–81]. These agents reduce mortality from cardiovascular events in both men and ...

2020年3月4日 · This Review provides an overview of haemostasis and thrombosis, details the current landscape of antithrombotic agents, addresses challenges with preventing thromboembolic events in patients at...