The asthma management cycle to minimize risk and control symptoms ...18 GINA recommendations for mild asthma ..... 20 Starting asthma treatment..... 21 Stepwise approach for adjusting treatment for individual patient needs....31

For individuals with moderate to severe persistent asthma already taking low- or medium-dose ICS, the preferred treatment is a single inhaler with ICS-formoterol (referred to as single maintenance and reliever therapy, or “SMART”) used both daily and as needed.

Use stepwise approach to identify appropriate treatment options (see page 7). Inhaled corticosteroids (ICSs) are the most effective long-term control therapy. When choosing treatment, consider domain of relevance to the patient (risk, impairment,

2020年12月3日 · Updated treatment diagrams that incorporate the new recommendations by age group and severity into the existing stepwise asthma management approach. Related News Thursday, December 3

The asthma management cycle to minimize risk and control symptoms...14 A major change in GINA 2019 recommendations for mild asthma.....16 Starting asthma treatment..... 17 Stepwise approach for adjusting treatment for individual patient needs....21

Preferred Treatment: • Increase inhaled corticosteroids within medium-dose range and add long-acting inhaled beta2-agonists. Alternative treatment (listed alphabetically): Increase inhaled corticosteroids within medium-dose range and add either leukotriene modifier or theophylline. Step 1 actions plus: • Teach self-monitoring

2022年10月5日 · Asthma severity is the intrinsic intensity of the disease process and dictates which step to initiate treatment. Asthma control is the degree to which the goals of therapy are met (e.g., pr event symptoms/exacerbations, maintain normal lung function and a ctivity levels).

Consider adding asthma biologics (includes anti-IgE, anti-IL5, anti-IL5R, anti-IL4/IL13) and * Before stepping up, adherence, environmental factors (eg, trigger exposure), and comorbid conditions should be reviewed and managed if needed.

The stepwise approach is meant to assist, not replace, clinical decision-making required to meet individual needs. Key: Alphabetical order is used when more than one treatment option is listed within either preferred or alternative therapy. ICS = inhaled corticosteroid;

The aim of asthma management is control of the disease. Complete control is defined as: - No daytime symptoms - No night time awakening due to asthma - No need for rescue medication - No exacerbations - No limitations on activity including exercise - Normal lung function (in practical terms FEV1 and/or PEF >80% predicted or best)