Proposed diagnostic criteria and classification of basophilic …
A next defined stage of basophil development is the basophilic myelocyte. Immature basophils, including basophilic myelocytes, exhibit a round nucleus and larger granules, whereas mast cell precursors usually have small-sized granules and, at a certain maturation stage, these cells exhibit bi- or poly-lobed nuclei . 46 In consecutive phases of ...
Proposed diagnostic criteria and classification of basophilic …
2017年1月16日 · Basophils form a distinct cell lineage within the hematopoietic cell family. In various myeloid neoplasms, including chronic myeloid leukemia, basophilia is frequently seen.
Basophilia - StatPearls - NCBI Bookshelf
2024年8月11日 · The earliest identifiable stage is a basophil myelocyte, which exhibits the characteristic basophil granules. These granules, measuring approximately 0.2 to 1 μm in diameter, are larger than the azurophilic granules found in promyelocytes and are often irregular.
Basophilic myeloblasts: a clue for CML blast phase
2021年5月20日 · Mature basophils were rarely found on blood and marrow smear in this patient. Instead, basophilic myeloblasts were seen. They expressed HLA-DR with CD123 (dimmer than that of mature basophils), initially preventing definitive identification by flow cytometry.
Basophilic blast phase of chronic myelogenous leukemia
2014年10月9日 · A 29-year-old man with an 8-year history of chronic myeloid leukemia (CML) was referred to our institution for marked leukocytosis and 3% blasts (white blood cells [WBC], 338.7 × 10 9 /L; neutrophils, 159.2 × 10 9 /L; myelocytes, 88.1 × 10 9 /L; basophils, 47.4 × 10 9 /L) (panel A). Cytogenetic studies showed t(9;22)(q34;q11.2), and the ...
Development of Basophils | Hematopoiesis - Histology Guide
Histology of developing basophils (basophilic myelocyte, basophilic metamyelocyte, and band basophils) in bone marrow.
Hematopoiesis - University of Oklahoma Health Sciences Center
The eosinophilic myelocyte is the most easily determined with its coarse eosinophilic granules. In the neurtrophilic myelocyte , neutrophilic granules are beyond the resolution of the light microscope.
Myelocyte - Wikipedia
A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).
Basophilia - PubMed
2024年8月11日 · The earliest identifiable stage is a basophil myelocyte, which exhibits the characteristic basophil granules. These granules, measuring approximately 0.2 to 1 μm in diameter, are larger than the azurophilic granules found in promyelocytes and are often irregular.
Immunophenotypic study of basophils by multiparameter flow ... - PubMed
Flow cytometric immunophenotyping can identify immunophenotypic aberrations of basophils in chronic myelogenous leukemia, and discriminate basophils from myeloblasts.