Bile acid metabolism and signaling in health and disease: …
2024年4月26日 · Biochemical synthesis and maturation of BAs. Schematic diagram depicting the biochemical synthesis of BAs. A prefix of G represents a glycine conjugate, while a prefix of T …
Bile Acid Synthesis, Metabolism, and Biological Functions
2024年10月7日 · Recent findings have demonstrated that bile acids are involved in the control of their own metabolism and transport via the enterohepatic circulation, regulate lipid metabolism, …
Bile acid biosynthesis - PubMed
1992年5月26日 · This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, …
Metabolic Messengers: bile acids | Nature Metabolism
2022年3月25日 · Bile acids (BAs) are amphipathic steroid acids whose production and diversity depend on both host and microbial metabolism. These metabolites have emerged as …
Novel bile acid biosynthetic pathways are enriched in the
2021年7月29日 · Here we show that centenarians have a distinct gut microbiome that is enriched in microorganisms that are capable of generating unique secondary bile acids, including …
Frontiers | Bile Acid Synthesis: From Nature to the Chemical ...
2018年9月24日 · In this paper, the different pathways of bile acid biosynthesis are explained as well as chemical modifications and the synthesis of different keto derivatives of BAs. Also, the …
Bile Acid Metabolism and Signaling - PMC - PubMed Central (PMC)
Bile acid synthesis generates bile flow and biliary secretion of bile acids, phospholipids, cholesterol, drugs, and toxic metabolites. Cholic acid (CA) and chenodeoxycholic acid (CDCA) …
The Biosynthesis, Signaling, and Neurological Functions of Bile Acids
Bile acids (BA) are amphipathic steroid acids synthesized from cholesterol in the liver. They act as detergents to expedite the digestion and absorption of dietary lipids and lipophilic vitamins.
Bile acid metabolism and signaling, the microbiota, and …
2022年9月1日 · Bacterial-transformed bile acids activate different bile acid receptors to regulate signaling pathways with broad coverage of complex symbiotic metabolism networks, including …
Bile acid metabolism and signaling - PubMed
Bile acids are important physiological agents for intestinal nutrient absorption and biliary secretion of lipids, toxic metabolites, and xenobiotics. Bile acids also are signaling molecules and …