000664 - B6 Strain Details - The Jackson Laboratory
C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.
C57BL/6 Mice | Charles River - Charles River Laboratories
The C57BL/6 mouse is a multipurpose model that can be used for research into physiology, immunology, safety and efficacy, oncology and genetics, as well as mouse model creation. B6 mice are often preferred to other inbred mice in certain research disciplines such as …
There is no such thing as a C57BL/6 mouse! - The Jackson Laboratory
Since C.C. Little (the founder of The Jackson Laboratory) initially generated the C57BL inbred strain in the 1920’s-1930’s, the inbred substrain C57BL/6 became the most frequently used mouse strain in biomedical research.
000664 - B6 Strain Details - The Jackson Laboratory
2019年1月3日 · C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.
MGI - Inbred Strains: C57BL - The Jackson Laboratory
C57BL is probably the most widely used of all inbred strains, (substrain C57BL/6 alone accounts for over 14% of occasions on which an inbred strain is used) though in many ways it seems to be atypical of inbred strains of laboratory mice.
The Genome of C57BL/6J “Eve”, the Mother of the Laboratory Mouse …
The inbred mouse strain C57BL/6 (B6) is the most commonly cited and well-characterized laboratory strain used in biomedical research.
The C57BL/6 mouse is a multipurpose model that can be used in such fields as model creation, physiology, safety and efficacy, and genetics. General Purpose - Atochina, E.N. et al. Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization.
C57BL/6 Strain Detail MGI Mouse MGI:2159769 - The Jackson …
2024年11月19日 · View mouse strain C57BL/6 : mutations, QTL, phenotypes, diseases, and references.
C57BL/6 strain shows an increased preference for narcotics and alcohol, so is preferentially used for genetic studies of substance abuse (Peirce et al., 1998).
Substrains matter in phenotyping of C57BL/6 mice - PMC
In this paper, we review recent reports of phenotypic and genetic differences among C57BL/6 substrains, focus our attention on the proper use of C57BL/6 and other inbred strains in the era of genome editing, and provide the life science research …
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