Characterized cre lines - The Jackson Laboratory
Transgenic cre activity, directed by the mouse aquaporin 2 promoter, is observed in kidney cells (collecting duct, left) and testes (sperm, right). Cre recombinase activity is expected in cholecystokinin positive neurons (interneurons) of the cortex.
Cre Portal - The Jackson Laboratory
The Cre Portal contains curated data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known recombinase activity patterns and allowing users to find relevant mouse resources for their studies.
Cre Mouse Lines | Disease Models | Services - Cyagen
Cyagen's drug screening and evaluation mouse model platform offers a wide range of Cre mouse lines, including regular Cre mice, inducible Cre mice, fluorescent reporter mice, etc., which may be used to develop a variety of cKO and cKI mouse models for your research study.
Cre transgenic mouse lines - PubMed
Over the past few years many inducible and/or tissue-specific Cre mouse lines have been developed. This chapter will give a brief review of the generation of Cre-expressing mouse lines and will discuss the strategy of using these Cre lines.
Cre Transgenic Mouse Lines - SpringerLink
2009年1月1日 · Cre transgenic mice can be produced by two methods (1) standard transgenesis with DNA pronuclear injection or, (2) knock-in approach with homologous recombination in ES cells.
Characterization of transgenic mouse lines expressing Cre …
2010年1月1日 · In this study, we examined and characterized the expression patterns of Cre recombinase in the retinas of 15 Cre-transgenic mouse lines. The Cre lines were chosen mainly based on their availability and known expression in neuronal or glial cells in the CNS.
Characterization of transgenic mouse models targeting ... - Nature
2019年10月11日 · Here, we present a systematic evaluation of mouse lines targeting neuromodulatory cells in the DR. We find substantial differences in specificity between lines targeting DA neurons, and in...
Generation of a ChAT Cre mouse line without the early onset hearing ...
2020年3月15日 · To develop ChAT Cre mice without accelerated hearing loss, we backcrossed ChAT IRES-Cre mice with CBA/CaJ mice that have normal hearing. We used genotyping to obtain mice homozygous for ChAT IRES-Cre and the wild-type allele at …
3.5 Cre-Lox, Driver Lines, and Next Order Specificity
What is the Cre-Lox system? What is the advantage of mouse Cre-driver lines? Examples of Cre-driver Lines used in neuroscience.
A Multifunctional Reporter Mouse Line for Cre- and FLP …
Here we report a new multifunctional Cre/FLP dual reporter allele (R26NZG) that exhibits strong and apparently ubiquitous marker expression in embryos and adults.