Chemotaxis - Wikipedia
Their most prominent member with chemotactic factor activity is leukotriene B4, which elicits adhesion, chemotaxis, and aggregation of leukocytes. The chemoattractant action of LTB4 is induced via either of two G protein–coupled receptors , BLT1 and BLT2 , which are highly expressed in cells involved in inflammation and allergy .
Chemotactic Factor - an overview | ScienceDirect Topics
Chemotactic factors direct the migration of immune cells, multipotent stem cells, and progenitor cells under physiologic and pathologic conditions. Chemokine ligand 12 and chemokine ligand 7 have been identified and investigated in multiple studies for their role in cellular trafficking in the setting of tissue regeneration.
Chemotactic Factor - an overview | ScienceDirect Topics
A chemotactic factor is a substance that stimulates the movement of specific immune cells, such as neutrophils and monocytes, towards sites of inflammation or infection. It can also enhance various cellular activities, including metabolic and microbicidal functions.
Chemotactic Factor - an overview | ScienceDirect Topics
The term chemotactic factor is used of molecules which stimulate the directional locomotion of cells in gradients. From: Encyclopedia of Immunology (Second Edition), 1998
Chemotaxis - Journal of Allergy and Clinical Immunology
Chemotaxis is the oriented or directed locomotion induced by a gradient of chemical substance. A variety of chemical substances or chemotactic factors for leukocytes are demonstrable, of which the most generally important are C5a and probably the lymphokines.
Chemotactic factors - SpringerLink
2016年2月5日 · Chemotactic factors 21 Accesses. Abstract. Substances regulating the directed movement of cells (chemotaxy). They are abbreviated as chemotaxins. Both endogenous and exogenous chemotaxins are recognised. The group of endogenous chemotaxins includes chemokines and several other cytokines, certain prostanoids and the fragments of certain …
Neutrophil chemotactic factors | SpringerLink
Neutrophil chemotactic factors include bacterial peptides (formylated methionine-leucine-phenylalanine), products of complement activation (C5a), extracellular matrix degradation products (laminin digests), arachidonic acid metabolites (leukotriene B4), other lipid mediators (platelet activating factors), and a number of small molecular weight ...
Chemotactic Factor - an overview | ScienceDirect Topics
Chemotactic factors govern the chemotaxis of various, and sometimes specific, inflammatory cells to the site of inflammation. From: Eosinophils in Health and Disease, 2013
Neutrophil Chemotaxis: Signaling and Movement Dynamics
2024年10月7日 · Among the most well-known chemotactic factors are chemokines, a family of small proteins that play a significant role in immune cell trafficking. Chemokines such as interleukin-8 (IL-8) are particularly effective in directing neutrophil movement, binding to specific receptors on the cell surface to initiate a cascade of intracellular events.
Neutrophil chemotactic factors | SpringerLink
Oxidative modification of methionine residues or changes in the amino acid sequence of peptide chemoattractants dramatically alter their chemoattractive properties. Many of the well-defined neutrophil chemotactic factors and studies of their structure …
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