Conjunctival intraepithelial neoplasia could be a fleshy, sessile or minimally elevated lesion that frequently appears perilimbal in the interpalpebral zone, or less commonly in the inferior fornix or palpebral conjunctiva. CIN can extend into the adjacent corneal epithelium.

Conjunctival intraepithelial neoplasia (CIN) is non- invasive by definition; the basement membrane remains intact and the underlying substantia propria is spared. It is a slow- growing tumor that arises from a single mutated cell on the ocular surface.

2016年9月15日 · Invasive conjunctival squamous cell carcinoma is often histologically preceded by conjunctival intraepithelial neoplasm (CIN), which represents the most frequently encountered conjunctival neoplastic growth.

2019年5月15日 · The general clinical term of OSSN includes a spectrum of malignancies that ranges from mild epithelial dysplastic changes, such as conjunctival intraepithelial neoplasia (CIN), to more severe invasive carcinoma that invades through the basement membrane into the substantia propria, such as squamous cell carcinoma.

To summarise the main causes and associations of conjunctival intraepithelial neoplasia (CIN) found in the literature to date. Literature search using Ovid databases on the NHS Scotland E‐library, Medline, and the Cochrane Library.

Squamous conjunctival neoplasia (SCN), said to make up 14% of all primary ocular and orbital tumors, is related to sun exposure, particularly UV-B radiation.

6 天之前 · The malignancies can range from conjunctival intraepithelial neoplasia (CIN) to squamous cell carcinoma. The squamous neoplasms have further been classified as noninvasive and invasive types. Pizzarello and Jakobiec first described the term CIN, which is similar to gynecologic tumor terminology of intraepithelial neoplasia.

Background: Conjunctival intraepithelial neoplasia (CIN) is the most common tumor of the ocular surface and is a precursor to invasive squamous cell carcinoma. CIN comprises a spectrum of premalignant epithelial neoplasia that usually begins near the limbus and spreads to the cornea.

Tumors were classified into 4 histological groups: conjunctival intraepithelial neoplasia (CIN) with mild dysplasia (grade 1/3), moderate dysplasia (grade 2/3), severe dysplasia (grade 3/3 or carcinoma in situ), and invasive squamous cell carcinoma (SCC).

Conjunctival intraepithelial neoplasia (CIN) in a patient with a history of basal cell carcinoma. He noticed a red lesion on his conjunctiva that developed over 4–5 months before presentation (Fig 1).