Exon skipping - Wikipedia
In molecular biology, exon skipping is a form of RNA splicing used to cause cells to “skip” over faulty or misaligned sections of genetic code, leading to a truncated but still functional protein …
What is exon skipping and how does it work? - Muscular ...
As the name suggests, the principle of exon skipping is to encourage the cellular machinery to ‘skip over’ an exon. Small pieces of DNA called antisense oligonucleotides (AOs) or ‘molecular …
What is Exon Skipping? - News-Medical.net
2021年5月7日 · Exon skipping splices a gene and restores its reading frame. It encourages the cellular machinery to “skip” over an exon by masking it with antisense oligonucleotides …
What is exon skipping and how does it work? - DMD Warrior
2024年10月4日 · What is Exon Skipping in DMD? The idea behind exon skipping therapy is to skip over deleted exons and merge them with the first available exon that can be spliced. With …
Exon Skipping - an overview | ScienceDirect Topics
Exon skipping refers to a genetic modification technique that induces the removal or exclusion of certain exons during the process of alternative splicing, resulting in the production of mRNA …
Exon Skipping - an overview | ScienceDirect Topics
Exon skipping is a genetic approach aimed at restoring the production of functional dystrophin protein in individuals with specific mutations in the DMD gene. This therapy mainly works by …
Exon Skipping - an overview | ScienceDirect Topics
Five major alternative splicing events are distinguished: exon skipping (also called cassette exon), use of alternative acceptor and/or donor sites, intron retention, and mutually exclusive exons. …