Fenproporex - Wikipedia
Fenproporex (Perphoxene) (N-2-Cyanoethylamphetamine) (3-(1-phenylpropan-2-ylamino)propanenitrile) (3-[(1-Methyl-2-Phenylethyl)amino]propiononitrile) is a stimulant drug of the phenethylamine and amphetamine chemical classes that was developed in the 1960s.
Fenproporex: Uses, Interactions, Mechanism of Action - DrugBank …
2007年7月31日 · Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency.
Safety and efficacy of fenproporex for obesity treatment: a …
Fenproporex produced additional weight reductions of 4.7 kg (one year), 3.8 kg (six months) and 1.55 kg (two months) in average, in relation to diet and exercise only (three trials). Insomnia, irritability, and anxiety were the most frequently reported side effects in the four studies.
Esbelcaps: Uses, Side Effects, Risks, Doses And More
2022年7月26日 · Esbelcaps capsules is an anorexigenic drug consisting of diazepam and fenproporex that is used to reduce appetite when you are suffering from very serious weight problems. For this drug to work, a person must follow a low-calorie diet during treatment.
Systematic review and meta-analysis of the efficacy and safety of ...
The aim of this study was to evaluate efficacy and safety of amfepramone, fenproporex and mazindol as a monotherapy for the treatment of obese or overweight patients. A systematic review of primary studies was conducted, followed by a direct meta-analysis (random effect) and mixed treatment comparis …
(PDF) Safety and efficacy of fenproporex for obesity treatment…
2016年5月24日 · Fenproporex, a compound with structural similarity to amphetamine and prescribed as an anorectic drug, is 60-80% converted to amphetamine in rats and humans (see review by Paumgartten, Pereira ...
Fenproporex - an overview | ScienceDirect Topics
To the best of our knowledge this meta-analysis is the most comprehensive assessment involving the main anorexigenic drugs that act on the central nervous system. The most studied drug is sibutramine (45 studies), and there were few data regarding fenproporex (2 studies). Mazindol had 5 RCTs included, 4 of which were from the 1970s.
Fenproporex | C12H16N2 | CID 61810 - PubChem
Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by …
Fenproporex - an overview | ScienceDirect Topics
Fenproporex, one of the lesser known anorectic drugs, is structurally related to amfetamine, to which it is rapidly metabolized after oral ingestion. Stimulatory effects, somnolence, and electroencephalographic abnormalities are reported to be the major undesired reactions (1). In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016.
Fenproporex (3-[(2-methyl-1-phenylpropan-2-yl)amino]propanenitrile), a compound structurally similar to amphetamine, was developed as an anorectic drug in the 1960s. Notwithstanding the structural resemblance, it was claimed that fenproporex (FEN) would be devoid of amphetamines’ stimulatory effects and thus it was recommended as
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