Fentanyl - Wikipedia
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. [12] [13] Fentanyl is also used as a sedative. [14]
Fentanyl | C22H28N2O | CID 3345 - PubChem
Fentanyl is a member of the class of drugs known as fentanyls, rapid-acting opioid (synthetic opiate) drugs that alleviate pain without causing loss of consciousness (analgesic). Fentanyl depresses central nervous system (CNS) and respiratory function. Exposure to …
Fentanyl - StatPearls - NCBI Bookshelf - National Center for ...
2023年5月29日 · Fentanyl is a potent synthetic opioid, which, similar to morphine, produces analgesia but to a greater extent. This robust pharmacologic agent is typically 50 to 100 times more potent. A dose of only 100 micrograms can produce equivalent analgesia to approximately 10 mg of morphine.
Fentanyl | C22H28N2O - ChemSpider
ChemSpider record containing structure, synonyms, properties, vendors and database links for Fentanyl, 437-38-7, PJMPHNIQZUBGLI-UHFFFAOYSA-N
Fentanyl-related compounds and derivatives: current status …
Fentanyl is a synthetic μ-opioid agonist with a wide margin of safety, readily reversible minimal effects on the cardiovascular and respiratory systems, and its congeners are key structures for a family of most promising powerful synthetic opioid analgesics used for managing pain during and after surgery, to treat patients with severe pain, or ...
This fact sheet provides information regarding characteristics of fentanyl and fentanyl analogs; the physical properties of fentanyl, fentanyl citrate, carfentanil, 3-methylfentanyl and α-methylfentanyl; potential exposure pathways; provisional advisory levels (PAL) and industry
Fentanyl drug profile | www.euda.europa.eu
Fentanyl is a narcotic analgesic with a potency at least 80 times that of morphine. Fentanyl and its derivatives (Alfentanil, Sufentanil, Remifentanil and Carfentanil) are used as anaesthetics and analgesics in both human and veterinary medicine (Carfentanil).
Fentanyl | Chem 13 News Magazine | University of Waterloo
Chemical name: N-phenyl-N- [1- (2-phenylethyl)piperidin-4-yl]propanamide. Formula: C 22 H 28 N 2 O. Molecular Weight: 336.47052 g/mol. Structure: Fentanyl is a synthetic, lipophilic phenylpiperidine derivative with both analgesic (painkiller) and anesthetic (causes reversible loss of consciousness) properties.
Fentanyl and Its Derivatives, Pharmacology, Use and Abuse, and ...
2024年2月20日 · From a number of newly synthesized molecular entities that showed significant analgesic activity, a substance called fentanyl appeared to be the most advantageous, the effects of which being about 80–100 times stronger than those of morphine.
Fentanyl Structure as a Scaffold for Opioid/Non-Opioid …
In the present contribution we summarize the attempts in which fentanyl or its substructures were used as a μ-opioid receptor pharmacophoric fragment and a scaffold to which fragments related to non-opioid receptors were attached.