What is fibrous dysplasia? Fibrous dysplasia is a long-term (chronic) problem in which scarlike tissue grows in place of normal bone. It is not cancer. It often results in one or more of these: Bone deformity. Brittle bones. Pain. Uneven growth of bones. Any bone can be affected. More than one bone can be affected at any one time.

Fibrous dysplasia is a benign (noncancerous) bone condition in which abnormal fibrous tissue develops in place of normal bone. As these areas of fibrous tissue grow and expand over time, they can weaken the bone—causing it to fracture or become deformed.

Fibrous dysplasia is a very rare [2] nonhereditary genetic disorder where normal bone and marrow is replaced with fibrous tissue, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture, deformity, functional impairment, pain, and the impingement of nerves. [3] .

Fibrous dysplasia can make your bones fragile and more susceptible to bone fractures (broken bones). It can affect any bone in your body, but most commonly affects your: Thigh bone (femur). Shin bone (tibia). Ribs. Skull (including your facial bones). Upper arm (humerus).

Fibrous dysplasia happens when a gene mutates (changes) while the baby is developing in the womb. The changes in the gene cause bone-forming cells to fail to mature. Instead, they produce abnormal fibrous tissue in certain bones.

2023年7月24日 · Fibrous dysplasia is a typically benign bone lesion characterized by intramedullary fibro-osseous proliferation secondary to altered osteogenesis. The polyostotic form often presents in childhood. Malignant transformation is rare, and remote radiation therapy has been reported as a risk factor.

Fibrous dysplasia happens when abnormal fibrous (scar-like) tissue replaces healthy bone. The disease can affect any bone in the body. Symptoms of fibrous dysplasia can include bone pain, misshapen bones, and broken bones.

Depending on the location and severity of symptoms, your doctor may order one of the following tests: X-rays. This is the most common test that doctors use to diagnose fibrous dysplasia. An x-ray can evaluate the bone structure for the disease and diagnose fractures and misshapen bones. Magnetic resonance imaging (MRI) or computed tomography (CT).