A substance is GABAergic if it produces its effects via interactions with the GABA system, such as by stimulating or blocking neurotransmission. A GABAergic or GABAnergic agent is any …

2023年2月13日 · GABAergic neurons are located when the hippocampus, thalamus, basal ganglia, hypothalamus, and brainstem. The balance between inhibitory neuronal transmission …

Here, we review the gene expression and regulatory mechanisms controlling the main steps of GABAergic neuron development: early patterning of the proliferative neuroepithelium, …

2019年6月20日 · The spectacular diversity of GABAergic neurons enables an elaborate division of labour in deploying a rich repertoire of inhibitory control mechanisms to shape highly nuanced …

Although they represent a minority of the total neocortical neuronal population, GABAergic interneurons are highly heterogeneous, forming functional classes based on their …

All GABAergic interneurons produce GABA, the hyperpolarizing action of which in the mature brain accounts for their definition as inhibitory neurons. GABAergic neurons form a …

2018年11月1日 · GABAergic neurons synthesize GABA from glucose and others precursors, including pyruvate and others amino acids. GABA is the main inhibitory neurotransmitter in …

Here, we review the gene expression and regulatory mechanisms controlling the main steps of GABAergic neuron development: early patterning of the proliferative neuroepithelium, …

2022年11月11日 · Understanding the phenotypic and functional diversity of cerebral cortical GABAergic neurons requires a comprehensive analysis of key transcriptional signatures and …

2013年4月1日 · GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the adult brain. Studies on GABAergic cells have focused almost exclusively on local interneurons …