Glutamate receptor - Wikipedia
Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation. Glutamate receptors are implicated in a number of neurological conditions.
Glutamate Receptors - Neuroscience - NCBI Bookshelf
Several types of ionotropic glutamate receptors have been identified. Three of these are ligand-gated ion channels called NMDA receptors, AMPA receptors, and kainate receptors (Figure 7.11C).
Glutamate, Glutamate Receptors, and Downstream Signaling …
Glutamate is a nonessential amino acid, a major bioenergetic substrate for proliferating normal and neoplastic cells, and an excitatory neurotransmitter that is actively involved in biosynthetic, bioenergetic, metabolic, and oncogenic signaling pathways.
Glutamate Receptor Ion Channels: Structure, Regulation, and …
Glutamate receptors are grouped into four distinct classes based on pharmacology and structural homology, including the AMPA receptors (GluA1–GluA4), the kainate receptors (GluK1–GluK5), the NMDA receptors (GluN1, GluN2A–GluN2D, GluN3A, and GluN3B), and the δ receptors (GluD1 and GluD2).
Biochemistry, Glutamate - StatPearls - NCBI Bookshelf
2022年12月19日 · Once in the cleft, glutamate binds to its reciprocal receptors precipitating either ion influx (ionotropic receptors) or signal transduction cascades (metabotropic receptors), which then activate second messengers, ultimately regulating …
Glutamate receptor ion channels: structure, regulation, and function ...
Glutamate receptors mediate fast excitatory synaptic transmission in the central nervous system and are localized on neuronal and non-neuronal cells. These receptors regulate a broad spectrum of processes in the brain, spinal cord, retina, and peripheral nervous system.
Presynaptic glutamate receptors: physiological functions and
2008年5月9日 · Glutamate acts on postsynaptic glutamate receptors to mediate excitatory communication between neurons. The discovery that additional presynaptic glutamate receptors can modulate...
Glutamate Receptor - an overview | ScienceDirect Topics
Glutamate receptors are a family of receptors found in the nervous system that play a crucial role in mediating excitatory synaptic transmission. They can be classified into NMDA and non-NMDA subtypes based on their binding to different agonists.
Glutamate-Related Biomarkers in Drug Development for …
GLUTAMATE RECEPTORS. Glutamate receptors are numerous and highly complex; more than 20 glutamate receptors have been identified in the mammalian central nervous system. They fall into two main categories, ionotropic (voltage sensitive) and metabotropic (ligand sensitive).
The structure and function of glutamate receptor ion channels
2002年2月1日 · New insights into the structures of glutamate receptor ion channels (iGluRs), combined with functional and biochemical data, can help us to understand how agonist binding triggers their...