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  1. ScienceDirect
    https://www.sciencedirect.com › science › article › pii

    Morphological and Molecular Characterization of Adult Midgut ...

    • ••
      The Drosophila midgut is divided into regions with distinct morphology and function… 展开

    Summary

    Although the gut is a central organ of Eumetazoans and is essential for organismal … 展开

    ScienceDirect
    Introduction

    The emergence of the gastrointestinal tract within the body cavity is one of the major innovations in animal evolution allowing the transition from an intracellular to an extracellular mo… 展开

    ScienceDirect
    Results

    An Anatomical Atlas of Adult Drosophila Midgut Regions
    We first generated an anatomical atlas of Drosophila midgut regions using a combination of … 展开

    ScienceDirect
    Discussion

    The Midgut Is Comprised of Six Morpho-Functionally Distinct Regions
    The midgut has previously been divided into three regions based on the presence of acid-secreting ce… 展开

    ScienceDirect
    Experimental Procedures

    Fly Stocks
    To perform the gene expression pattern analysis, the F1 progeny derived from crosses between UAS-nlsGFP flies and Gal4 enhancer tr… 展开

    ScienceDirect
    How to make DAPI solution?
    1. Prepare a stock solution of 1 mg/ml DAPI by diluting in autoclaved milliQ water. 2. Store the solution in 1.5 ml amber coloured tube in 4 °C. 3. Make the working solution of 1 μg/ml, by taking 1 μl of stock solution, and dilute it with 1 ml of 1x PBS. Keep the solution in a 1.5 ml amber tube at 4 °C. 1.
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    目录
    Summary
    Introduction
    Results
    Discussion
    Experimental Procedures
    How to make DAPI solution?
     
  1. Nature
    https://www.nature.com › articles

    Drosophila activins adapt gut size to food intake and promote ...

  2. Nature
    https://www.nature.com › articles

    Gut cytokines modulate olfaction through metabolic

    2021年7月21日 · Our findings identify adaptive glial metabolic reprogramming by gut-derived cytokines as a mechanism that causes lasting changes in a sensory system in ageing flies.

  3. ScienceDirect
    https://www.sciencedirect.com › science › article › pii

    Contraction of gut smooth muscle cells assessed by

  4. nature.com
    https://www.nature.com › articles

    Spatially restricted immune and microbiota-driven adaptation of the gut

  5. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Quantitative Imaging of Gut Microbiota Spatial Organization

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    Does dapiglutide reduce intestinal insufficiency?
    In conclusion, the combined effects of decreased intestinal motility and well-balanced intestinal growth by the dual GLP-1R and GLP-2R agonist dapiglutide attenuate intestinal insufficiency in the murine SB model. To further substantiate the role of dapiglutide in the treatment of SBS, a clinical trial is warranted.

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    aspenjournals.onlinelibrary.wiley.com
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    Dapiglutide, a novel dual GLP‐1 and GLP‐2 receptor agonist, attenuates …

    aspenjournals.onlinelibrary.wiley.com
    How to make DAPI solution?
    1. Prepare a stock solution of 1 mg/ml DAPI by diluting in autoclaved milliQ water. 2. Store the solution in 1.5 ml amber coloured tube in 4 °C. 3. Make the working solution of 1 μg/ml, by taking 1 μl of stock solution, and dilute it with 1 ml of 1x PBS. Keep the solution in a 1.5 ml amber tube at 4 °C. 1.

    Methodology to Detect the Abnormality of Drosophila Gut by Various

    link.springer.com
    Does DAPI fade faster than other dyes?
    DAPI fades faster than other dyes [ 34 ]. DAPI staining is useful to identify the layering of the gut and if there is any fragmentation of nuclei within the gut. The current protocol uses various dyes to detect the structural, elemental as well as the stress level of the gut.

    Methodology to Detect the Abnormality of Drosophila Gut by Various

    link.springer.com
    How does Daw affect resizing of the gut?
    Consistent with the role of Daw in coupling adaptive resizing of the gut with nutrient availability, knockdown of its receptor, Babo-C, in progenitor cells reduced tissue turnover (Fig. 4j–l), prevented normalization of EB numbers (Fig. 4f–h), and impaired resizing of the gut in refed animals (Fig. 4i).

    Drosophila activins adapt gut size to food intake and promote

    nature.com
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    Strong hypertrophy in response to dapiglutide was noted on macroscopic inspection of the small intestine at autopsy, and even a significant elongation of the small intestine was detected. In line with this, intestinal dry weight was significantly increased in dapiglutide-treated ICR mice.

    Dapiglutide, a novel dual GLP‐1 and GLP‐2 receptor agonist, attenuates …

    aspenjournals.onlinelibrary.wiley.com
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  7. Cell Press
    https://www.cell.com › cell-reports › pdf
    [PDF]

    Cell Reports Resource - Cell Press

  8. Nature
    https://www.nature.com › articles
    [PDF]

    Mechanically enhanced biogenesis of gut spheroids with

  9. Springer
    https://link.springer.com › protocol

    Methodology to Detect the Abnormality of Drosophila Gut by …

  10. epfl.ch
    https://flygut.epfl.ch › histology

    Flygut - EPFL