HaCaT cells as a model system to study primary cilia in keratinocytes
Spontaneously immortalized human keratinocytes, HaCaT are a model to study the epidermal homeostasis and pathophysiology. In contrast to what has been previously described, here, we show that HaCaT can be efficiently ciliated.
Growth and differentiation of HaCaT keratinocytes - PubMed
HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation. Under typical culture conditions HaCaT cells have a partially to fully differentiated phenotype due …
Cellosaurus cell line HaCaT (CVCL_0038)
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature. Short tandem repeat profiling provides an international reference standard for human cell lines.
HaCaT Cells - Cytion
HaCaT cells are a pivotal model in dermatological research, offering insights into the complex mechanisms of skin biology and pathology. The spontaneously immortalized HaCaT cell line is derived from adult human epidermal cells and retains the capacity t…
HaCaT Cell Line - Exploring Skin Biology and Disease - Cytion
HaCaT cells are a spontaneously immortalized human keratinocyte cell line originating from adult skin and representing a unique evolutionary pathway. These cells possess mutations in both alleles of the p53 gene, which is typical for mutations induced by UV radiation [3,4].
The Overexpression of Epidermal Growth Factor (EGF) in HaCaT …
In view of above evidence, we aimed to explore the role of EGF produced by HaCaT cells in the proliferation, invasion, migration and transdifferentiation of ADSCs into epidermal cell phenotypes. Our study provides supporting evidences for ADSCs to …
Growth and Differentiation of HaCaT Keratinocytes
2013年10月24日 · HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation. Under typical culture conditions HaCaT cells have a partially to fully differentiated phenotype due to the high calcium...
HaCaT Cells as a Reliable In Vitro Differentiation Model to ... - PubMed
To standardize the in vitro studies on keratinocytes, we investigated the use of HaCaT cells, a long-lived, spontaneously immortalized human keratinocyte line which is able to differentiate in vitro, as a suitable model to follow the release of inflammatory and repair mediators in response to TNFα or IL-1β. Different treatment conditions ...
HaCaT - an overview | ScienceDirect Topics
HaCaT cells are a human epidermal keratinocyte line that has been used for investigation of multistep carcinogenesis in human cells (Boukamp et al. 1988). HaCaTs retain epidermal keratins characteristic of the more differentiated cell layers of human epidermis in vivo and are useful for in vivo analysis ( Breitkreutz et al. 1991 ).
HaCaT Keratinocytes and Primary Epidermal Keratinocytes Have …
HaCaT cells are the immortalized human keratinocytes and have been extensively used to study the epidermal homeostasis and its pathophysiology. T helper cells play a role in various chronic dermatological conditions and they can affect skin barrier homeostasis.
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