Hereditary nonpolyposis colorectal cancer - Wikipedia
Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer. HNPCC includes (and was once synonymous with) [ 1 ] Lynch syndrome , an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary , stomach , small intestine ...
Hereditary Nonpolyposis Colorectal Cancer (HNPCC) - Cleveland Clinic
Hereditary nonpolyposis colorectal cancer (HNPCC) is a type of colorectal cancer caused by genetic changes (mutations) that run in families. Healthcare providers treat HNPCC with surgery and systemic therapies like chemotherapy and immunotherapy (when needed).
Lynch syndrome - Symptoms and causes - Mayo Clinic
2024年3月8日 · Lynch syndrome used to be called hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC is a term used to describe families with a strong history of colon cancer. Lynch syndrome is the term used when doctors find a gene that runs in the family and causes cancer.
Hereditary Nonpolyposis Colon Cancer - StatPearls - NCBI Bookshelf
2023年7月16日 · Hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an autosomal dominant disorder. Individuals with HNPCC are at increased risk for synchronous and metachronous colorectal cancer (CRC). The most common extracolonic manifestation in HNPCC is endometrial cancer.
A Review of Hereditary Colorectal Cancers - StatPearls - NCBI Bookshelf
2022年9月26日 · Hereditary Colorectal Polyposis and Cancer Syndromes: A Primer on Diagnosis and Management. Am J Gastroenterol. 2017 Oct;112(10):1509-1525. [PubMed] 5.
Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
2019年10月23日 · The most common hereditary form of colorectal cancer is Lynch syndrome, also called hereditary nonpolyposis colorectal cancer (HNPCC). Identifying patients with Lynch syndrome is important because their lifetime risk of colorectal cancer is 80%, and up to 60% for endometrial cancer.
What Is Hereditary Nonpolyposis Colorectal Cancer (HNPCC)?
2024年9月9日 · Hereditary nonpolyposis colorectal cancer (HNPCC) is inherited and increases your risk of colorectal cancer. Learn about symptoms, diagnosis, treatment, and more.
Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch …
Hereditary nonpolyposis colorectal cancer HNPCC, Lynch syndrome) is a genetic disease of autosomal dominant inheritance. It is caused by a mutation in one of four genes of the DNA mismatch repair system and confers a markedly increased risk for various types of cancer, particularly of the colon and the endometrium.
Lynch Syndrome - Johns Hopkins Medicine
Also known as hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, Lynch syndrome was first described more than 100 years ago. It is the most common of the recognized inherited colon and rectal cancer syndromes. Many patients with colon or rectal cancer experience no symptoms in the early stages of the disease.
HNPCC (Hereditary Nonpolyposis Colorectal Cancer)
2022年8月29日 · The most common cause of inherited colon cancer is Lynch syndrome, also called hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC may also increase the risk of developing other cancers at an earlier age, including ovarian, endometrial, esophageal, stomach, liver, kidney, small intestine, urinary tract, prostate, brain, and skin cancers.