Histidine operon leader - Wikipedia
The Histidine operon leader is an RNA element found in the bacterial histidine operon. At least 6 amino acid operons are known to be regulated by attenuation. [1] In each a leader sequence of 150–200 bp is found upstream of the first gene in the operon.
Attenuation regulation of amino acid biosynthetic operons in ...
2006年1月9日 · Histidine biosynthetic operons his were predicted to be regulated by histidine-dependent attenuators in Bacillus cereus and Clostridium difficile, and by histidine T-boxes in L. lactis and Streptococcus mutans.
Evolution of transcriptional regulation of histidine metabolism in …
2022年8月25日 · The histidine biosynthesis genes are organized into compact his operons in many Gram-negative and Gram-positive bacteria, although the operon content and gene order are different between the major bacterial phyla.
The Origin and Evolution of Operons: The Piecewise Building of …
Except for the first gene of the operon, hisG (which is regulated by the final product, histidine), the three gene blocks (hisDCN, BHAF, and IE) code for proteins operating in the reverse order in the metabolic pathway.
The Operon as a Conundrum of Gene Dynamics and Biochemical …
2023年4月21日 · Histidine biosynthesis is a highly studied metabolic pathway, and many of the models suggested to explain operons origin and evolution can be applied to the histidine pathway, making this route an attractive model for the study of operon evolution.
The Histidine Operon Is Ancient | Journal of Molecular Evolution
2006年4月11日 · This broad phylogenetic distribution suggests that the unified histidine operon is ancient. Consistent with the hypothesis of a single origin, hisDBHAFI are in the same relative order in all of these groups except the Crenarchaeota.
The Biosynthesis of Histidine and Its Regulation
2010年1月1日 · All the genes of histidine biosynthesis are adjacent and form an operon located at 44 min on the E. coli chromosome. The enzyme called phosphoribosyl-phosphate-ATP-pyrophosphorylase (PR-ATP-pyrophosphorylase for short, hisG ) catalyzes a Mg ++ dependent reaction between ATP and 5-phosphoribosyl-1-pyrophosphate (PRPP) to give N1-(5 ...
CDD Conserved Protein Domain Family: His_leader - National …
This family consists of the leader peptide of the histidine (his) operon. The his operon contains all the genes necessary for histidine biosynthesis.
The Operon as a Conundrum of Gene Dynamics and Biochemical …
2023年4月21日 · Histidine biosynthesis is a highly studied metabolic pathway, and many of the models suggested to explain operons origin and evolution can be applied to the histidine pathway, making this route an attractive model for the study of operon evolution.
Histidine - His - structure, properties, function, benefits
2023年11月22日 · Histidine is usually referred to as a semi-essential amino acid because it is nonessential in adults but is essential in the diet of infants and individuals with uremia - a kidney disorder. Our body mostly needs Histidine to regulate and to utilize essential trace elements like iron, copper, molybdenum, zinc, and manganese.