Treatment of acute hyperammonemia focuses on decreasing the level of ammonia and controlling specific complications, including brain swelling (cerebral edema) and pressure around the brain (intracranial hypertension).

2023年4月7日 · Hyperammonemia should be recognized early and treated immediately to prevent the development of life-threatening complications such as cerebral edema and brain herniation. Treatment strategies vary according to etiology.

2023年2月17日 · High ammonia levels in the blood often indicate a problem with the liver. Doctors can provide treatment, including sodium benzoate and transplants. Learn more here.

The treatment choice should be based on the symptoms, ammonia levels and, on the most likely diagnosis depending on previous knowledge or urgent laboratory results. Table 4 summarizes the drugs that are useful in the treatment of hyperammonaemia.

2023年4月20日 · Treatment is adjusted according to a person’s age and what causes their hyperammonemia. Possible treatments include : hemodialysis, hemofiltration, and intravenous medications for...

Because only a small number of patients with severe acute liver failure or other conditions associated with hyperammonemia actually present with cerebral edema, there are few published studies that clarify the role of extracorporeal dialysis treatment in reducing blood ammonia levels and thereby, potentially treating the cerebral edema.

The current therapeutic options to treat hyperammonemia target either the reduction of ammoniagenesis and its absorption in the gastrointestinal (GI) tract, or the activation of ammonia removal by upregulating ureagenesis through treatment with N-carbamylglutamate or supplementation of urea cycle intermediates and glutamine synthesis . First ...

Medications used to treat hyperammonemia include: Lactulose: This medication helps reduce ammonia levels by promoting its excretion through the stool. Antibiotics: Certain antibiotics, such as rifaximin, can reduce the production of ammonia by gut bacteria.

2021年9月28日 · The aims of treatment for hyperammonemia are to correct biochemical abnormalities and ensure adequate nutritional intake. Treatment involves compounds that increase the removal of...

2022年4月11日 · Even slightly elevated levels (hyperammonemia) are toxic to your central nervous system (CNS). What are normal ammonia levels? Normal blood levels of ammonia vary according to age and are higher in newborns compared to older children or adults. In newborns, gestational and postnatal ages also affect the levels of ammonia.