Immune checkpoint inhibitors are a type of immunotherapy that block immune checkpoint proteins from binding with partner proteins. Learn about the cancers treated with checkpoint inhibitors and the side effects they may cause.

Immune checkpoint inhibitors, like PD-1 or PD-L1 inhibitors, are treatments that help the immune system recognize and attack cancer cells. Learn more here.

Checkpoint inhibitor therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated can dampen the immune response to an immunologic stimulus. Some cancers can protect themselves from attack by stimulating immune checkpoint targets.

Immune checkpoint inhibitors stop the immune system from turning off before cancer is completely eliminated. They’re a type of immunotherapy. The immune system relies on T cells to fight cancer. These specialized cells are extremely …

2024年11月14日 · Immune checkpoint inhibitors (ICIs), also known as checkpoint inhibitor immunotherapy, are immunomodulatory antibodies that are used to enhance the immune system. These agents have substantially improved the prognosis for patients with many advanced malignancies. The primary targets for checkpoint inhibition include (table 1):

2024年2月5日 · Immune checkpoint inhibitors work by blocking checkpoint proteins – including CTLA-4, PD-L1 and PD-1 – on the surface of T cells. These proteins normally prevent T cells from attacking healthy cells, but treatment with checkpoint inhibitors unleashes the T cells to eliminate cancer cells more effectively.

Checkpoint inhibitors are a type of immunotherapy that block different checkpoint proteins. Examples include pembrolizumab (Keytruda) and ipilimumab (Yervoy).

Checkpoint inhibitors are designed to improve the immune system’s ability to destroy cancer cells by switching off checkpoints, a type of protein that controls immune responses. Checkpoint inhibitor drugs are a type of monoclonal antibody .

A type of drug that blocks proteins called checkpoints that are made by some types of immune system cells, such as T cells, and some cancer cells. These checkpoints help keep immune responses from being too strong and sometimes can keep T cells from killing cancer cells.

Checkpoint inhibitors work by releasing a natural brake on your immune system so that immune cells called T cells recognize and attack tumors.