Initial Invasive or Conservative Strategy for Stable Coronary Disease
2020年3月30日 · We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial...
ISCHEMIA Trial | Circulation - AHA/ASA Journals
2020年4月22日 · Ischemia Trial: What Have we Learned? The results of ISCHEMIA provide new data in patients with SIHD and moderate to severe ischemia treated with contemporary GDMT and revascularization techniques. We have learned that an invasive strategy is not associated with a reduction in cardiovascular mortality or MI.
Outcomes in the ISCHEMIA Trial Based on Coronary Artery …
2021年9月9日 · In the ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) of stable ischemic heart disease, severity of coronary artery disease (CAD), but not ischemia severity, predicted 4-year mortality.
International Study of Comparative Health Effectiveness With Medical ...
2023年11月11日 · The ISCHEMIA trial failed to show that routine invasive therapy was associated with a reduction in major adverse ischemic events compared with optimal medical therapy among stable patients with moderate ischemia.
ISCHEMIA Trial
What is the ISCHEMIA Trial? An NHLBI-funded international comparative effectiveness trial to determine the best way to treat chronic coronary disease. Patients with moderate or severe ischemia, with or without stress imaging, were eligible for participation.
Initial Invasive or Conservative Strategy for Stable Coronary Disease
2020年4月9日 · Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial …
Health-Status Outcomes with Invasive or Conservative Care in …
2020年3月30日 · In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or...
Initial Invasive Versus Conservative Management of Stable Ischemic ...
2020年8月29日 · Whether an initial invasive strategy in patients with stable ischemic heart disease and at least moderate ischemia improves outcomes in the setting of a history of heart failure (HF) or left ventricular dysfunction (LVD) when ejection fraction is …
2020年3月30日 · We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial...
ISCHEMIA trial: How to apply the results to clinical practice
This study was the ISCHEMIA trial, a large, multicentric trial sponsored by the National Heart, Lung, and Blood Institute. The main trial compared coronary revascularization and optimal medical treatment (OMT) vs OMT alone in 5179 patients enrolled after a stress test.
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