Kinin are short lived peptides that cause pain sensation, arteriolar dilation, increase vascular permeability and cause contractions in smooth muscle. Kinins transmit their effects through G protein- coupled receptors.

Kinins are peptide hormones that transmit their biological effects via G protein – coupled receptors. The kinins have been implicated in the regulation of blood pressure, pain sensation and cell growth 2.

Kinins are plasma proteins that increase vascular permeability, interact with prostaglandins to cause pain and smooth muscle contraction and to increase the migration of white blood cells during the inflammatory process, and act as potent renal vasodilators to increase the renal excretion of sodium.

Kinins are proteins in the blood that cause inflammation and affect blood pressure (especially causing blood pressure to go down).

The meaning of KININ is any of various polypeptide hormones that are formed locally in the tissues and cause dilation of blood vessels and contraction of smooth muscle.

Kinins are the pharmacologically active peptides cleaved from kininogens by kallikreins, a heterogeneous class of proteases with two main representatives, plasma kallikreins and tissue kallikreins.

This review addresses the physiological role of the kallikrein–kinin system in arteries, heart and kidney and the consequences of kallikrein and kinin actions in diseases affecting these organs, especially ischemic and diabetic diseases.

Kinins are bioactive peptides generated in the inflammatory milieu of the tissue microenvironment, which is involved in cancer progression and inflammatory response. Kinins signals through activation of two G-protein coupled receptors; inducible Bradykinin Receptor B1 (B1R) and constitutive receptor B2 (B2R).

2022年1月1日 · Kinins are a group of short-lived proinflammatory peptide hormones that bind to G-protein-coupled receptors and trigger Ca 2+ -dependent nitric oxide and/or prostaglandin-dependent signaling pathways. Inflammation. Nociception. Blood pressure. Edema.

Kinins, including bradykinin and kallidin, are peptides that are produced and act at the site of tissue injury or inflammation. They induce a variety of effects via the activation of specific B1 or B2 receptors that are coupled to a number of biochemical transduction mechanisms.