Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase. [1][2][3]

2021年6月2日 · Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease.

Acute asthma attacks are often triggered by allergens or exercise. Inflammatory molecules called leukotrienes are one of several substances which are released by mast cells during an asthma attack, and it is leukotrienes which are primarily responsible for the bronchoconstriction.

2024年2月20日 · Leukotriene modifiers work by blocking the action of leukotrienes, one cause of the inflammation and nasal congestion associated with allergies. For those with allergies and asthma, leukotriene...

2020年3月11日 · Leukotrienes are fatty immune system chemicals that come from dietary omega-3 and omega-6 fatty acids. They play a key role in some of the more severe symptoms of allergic rhinitis and...

Leukotrienes (LTs) are lipid mediators that play pivotal roles in acute and chronic inflammation and allergic diseases. They exert their biological effects by binding to specific G-protein-coupled receptors. Each LT receptor subtype exhibits unique functions and expression patterns.

Leukotriene modifiers prevent the action of leukotrienes in the body. Leukotrienes are substances that are released from mast cells, basophils and eosinophils. These substances cause airway constriction (a narrowing of the airways), increased mucus …