Pathogenesis of HIV Infection - PubMed Central (PMC)
One mechanism HIV weakens the immune system is by infecting and destroying CD4+ T cells, which in turn leads to immunodeficiency at later stage of disease. 5 HIV attaches to the CD4+ …
Pathophysiology of HIV/AIDS - Wikipedia
HIV is commonly transmitted via unprotected sexual activity, blood transfusions, hypodermic needles, and from mother to child. Upon acquisition of the virus, the virus replicates inside and …
Human Immunodeficiency Virus (HIV) Infection - The Merck …
2024年5月7日 · Human immunodeficiency virus (HIV) infection (infection with either HIV-1 or HIV-2) destroys CD4+ lymphocytes and impairs cell-mediated immunity, increasing risk of certain …
Pathogenesis of human immunodeficiency virus infection
HIV is transmitted primarily through blood and genital fluids and to newborn infants from infected mothers. The steps occurring in infection involve an interaction of HIV not only with the CD4 …
Human Immunodeficiency Virus (HIV) Infection - MSD Manuals
HIV is transmitted through exchange of bodily fluids (semen, vaginal fluid, blood, breast milk) with an infected person, usually through vaginal or anal sex, sharing needles, or from mother to …
HIV infection | Nature Reviews Disease Primers
2015年10月1日 · Through mechanisms that are probably multidimensional and still not fully defined, HIV causes progressive loss of CD4 + T cells and a host of immunological …
Immunopathogenic Mechanisms of HIV Infection - National …
One of the early hallmarks of HIV infection, prior to the profound depletion in CD4+ T cells, is the impairment of a variety of CD4+ T-cell functions including T-cell colony formation, autologous …
Mechanisms of HIV-1 cell-to-cell transmission and the …
In this review we will discuss general cell contact-dependent mechanisms that HIV-1 utilizes for its spread and the evidence pointing to cell-to-cell transmission as a mechanism for the …
Pathogenic mechanisms of HIV disease - PubMed
Human immunodeficiency virus (HIV) infection is generally characterized by inefficient viral transmission; an acute phase of intense viral replication and dissemination to lymphoid …
HIV infection - Nature Reviews Disease Primers
2023年8月17日 · This Primer by Bekker and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of HIV infection, and discusses patient quality of life and …