Monocerin - Wikipedia
Monocerin is a dihydroisocoumarin and a polyketide metabolite that originates from various fungal species. It has been shown to display antifungal, plant pathogenic, and insecticidal characteristics. Monocerin has been isolated from Dreschlera monoceras, D. ravenelii, Exserohilum turcicum, and Fusarium larvarum. [1]
Monocerin | C16H20O6 | CID 92267 - PubChem
Monocerin | C16H20O6 | CID 92267 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Monocerin - an overview | ScienceDirect Topics
Bioactive isocoumarins monocerin (69) and analogs (e.g., 70) have been isolated from the endophytic fungus Microdochium bolleyi associated to the herbaceous plant F. cretica [111]. The compounds showed good antifungal, antibacterial, and antialgal activities and were also previously known as insecticidal.
Effect of Monocerin, a Fungal Secondary Metabolite, on …
2023年5月18日 · Monocerin increased cell proliferation and did not induce cell senescence. Morphological analysis showed cellular integrity. The study demonstrates aspects of the mechanism of action of monocerin on endothelial cell proliferation, suggesting the possibility of its pharmaceutical application, such as in regenerative medicine.
Monocerin | 抗感染试剂 | MCE
Monocerin 是从 Microdochium bolleyi 中分离出来的，它是一种来自 Fagonia cretica 的内生真菌。 Monocerin 对 Microbotryum violaceum、Escherichia coli、Bacillus megaterium 和 Chlorella fusca 显示出良好的抗真菌、抗菌和抗藻类活性 。
Enantioselective Total Synthesis of (+)-Monocerin, a …
2019年5月5日 · We describe here the enantioselective synthesis of (+)-monocerin and its acetate derivative. The present synthesis features an efficient optically active synthesis of the β-hydroxy-γ-lactone derivative with high enantiomeric purity using a …
Synthesis of monocerin, an antifungal, insecticidal and phytotoxic ...
1989年1月1日 · Monocerin (1 a) was first isolated by Aldridge and Turner as an antifungal metabolite from culture filtrates of Exerohilum monoceras Drechsler (= Drechslera monocerus = Helm inthosporium monoceras), which protect wheat against powdery mildew (Erisyphe graminis).1 Subsequently, Grove and Pople indentified 1a as an insecticidal constituent of the ...
Asymmetric total synthesis of (+)-monocerin - ScienceDirect
2013年11月20日 · A concise asymmetric total synthesis of (+)-monocerin has been accomplished. The cis-fused furobenzopyranone of monocerin was efficiently constructed via a Lewis acid-mediated stereoselective cyclization of 1,2,4-triols intermediate.
Synthesis and Incorporation of the First Polyketide Synthase Free ...
2004年1月27日 · These results provide evidence for the role of 1 as the first enzyme-free intermediate in the monocerin biosynthesis pathway and, thus, as the final product of the polyketide synthase (PKS) catalyzed part of the pathway. Compound 1 may therefore be of use in further studies to isolate and sequence the monocerin PKS gene.
Monocerin, a Phytotoxin from Exserohilum turcicum (≡ Drechslera …
1982年11月1日 · Monocerin inhibited seedling growth both of johnsongrass and, to a lesser extent, cucumber. The phytotoxic nature of this compound has not been described previously. Its activity against leaf tissue of two other species, from …
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