Esophageal Cancer: Insights From Mouse Models - PMC
In this review, we describe how different mouse models are used to study esophageal cancer. Keywords: esophagus, squamous cell cancer, adenocarcinoma, xenograft, tumor formation, …
Cellular heterogeneity in the mouse esophagus implicates the ...
In this study, we showed that basal cells in the mouse esophagus contained a heterogeneous population of epithelial cells, similar to other rapidly cycling tissues such as the intestine or skin.
Genetic Mouse Models and Induced Pluripotent Stem Cells for ...
Mouse models represent an insightful tool in revealing key signaling molecules and molecular pathways regulating esophagus development. However, there are structural and physiological …
Lgr5 marks stem/progenitor cells contributing to epithelial ...
2024年8月21日 · Here, authors identify Lgr5+ cells in the developing mouse esophagus and reveal their crucial role in epithelial and muscle development.
Single-cell transcriptomics uncovers the differentiation of a ...
2023年3月8日 · In this study, we profiled mouse esophagus by single-cell RNA sequencing and found taste buds specifically in the cervical segment of the esophagus. These taste buds have …
Isolation and characterization of mouse and human esophageal ...
2012年1月12日 · This protocol describes the isolation and characterization of mouse and human esophageal epithelial cells and the application of 3D organotypic culture (OTC), a form of …
The development and stem cells of the esophagus - PMC
First, the human esophagus is composed of more layers of both basal and suprabasal cells. In the adult mouse esophagus, the epithelium contains four to six layers of cells, whereas there are …