- Nicotinic acetylcholine receptorsNicotine mainly shows its action through specific nicotinic acetylcholine receptors located in brain. It stimulates presynaptic acetylcholine receptors thereby enhancing Ach release and metabolism.pmc.ncbi.nlm.nih.gov/articles/PMC7163392/
Molecular mechanisms for nicotine intoxication - ScienceDirect
- 已发布: 2019/05/01
- DOI: 10.1016/j.neuint.2019.02.006
- Keywords: Acute nicotine intoxication; Chronic nicotine int…
- 页数: 10
Nicotine, one of the more than 4700 ingredients in tobacco smoke, is a neurotoxin and once used as pesticides in agriculture. Although its use in agriculture is prohibited in many countries, nicotine intoxication is still a problem among the workers in tobacco farms, and young children as well as ad...Nicotine Addiction: Neurobiology and Mechanism - PMC
Nicotine shows a close resemblance to other addictive drugs in molecular, neuroanatomical and pharmacological, particularly the drugs which enhances the cognitive functions. Nicotine mainly shows its action through specific nicotinic …
Molecular mechanisms for nicotine intoxication - PubMed
Understanding the mechanism of nicotine intoxication is important not only for the prevention and treatment but also for the appropriate regulatory approaches. Here, we review …
Molecular and cellular mechanisms of action of nicotine in the CNS
Nicotine achieves its psychopharmacological effects by interacting with nicotinic acetylcholine receptors (nAChRs) in the brain. There are numerous subtypes of nAChR that differ in their …
- 作者: Jacques Barik, Susan Wonnacott
- Publish Year: 2009
Molecules and circuits involved in nicotine addiction: the many …
Integration of systems level effects of nicotine: common and disparate molecular mechanisms. It is now very clear that the nicotine in tobacco interacts with nAChRs in the brain, and alters …
Nicotine: from molecular mechanisms to behaviour - PubMed
Nicotine, like other addictive drugs including psychomotor stimulants, promotes dopamine release in the nucleus accumbens. This transmitter system has been a major focus of both …
Nicotine Chemistry, Pharmacology, and Pharmacokinetics
2016年1月1日 · This chapter describes the basic chemical structure and function of nicotine, the major alkaloid found in tobacco. Structurally related to the endogenous neurotransmitter …
Nicotine: from molecular mechanisms to behaviour
2005年2月1日 · A major goal in nicotine addiction research is to identify the molecular mechanisms underlying long-lasting behavioural alterations induced by nicotine, in brain …
understanding the various mechanisms and factors involved in the different aspects of nicotine dependence is crucial to develop successful prevention and intervention approaches, including …
Nicotinic Receptors: Role in Addiction and Other Disorders of the …
Potential mechanisms underlying nicotine addiction. The fact that nicotine is an addictive drug is no longer in dispute, if it ever was. ... Molecular mechanisms of drug addiction. J Neurosci. …
- 某些结果已被删除
