Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details.

Confocal imaging eliminates background, improves signal-to-noise ratio, and protects live cell samples by reducing photobleaching and phototoxicity, for more reliability in both 2D and 3D imaging. Custom-designed optics, including barcoded emission filters and objectives, deliver both sensitive imaging and error-free operation.

From everyday assays to more demanding applications, the Operetta CLS high-content analysis system delivers just the right combination of flexible excitation, sensitive optics, and advanced software features to enable you to gain deeper biological insight from all your critical applications.

From everyday assays to more demanding applications, the Operetta CLS high-content analysis system delivers just the right combination of flexible excitation, sensitive optics, and advanced software features to enable you to gain deeper biological insight from all your critical applications.

With the Operetta CLS, you can choose from fluorescent widefield and confocal spinning-disk imaging with up to eight high-power excitation sources and user-accessible emission filters for maximum flexibility – so you can optimize your assays quickly.

Equipped with water immersion objectives and Harmony ® 4.8 high-content imaging and analysis software, the Operetta CLS is able to overcome the most critical of challenges with 3D assays and provides an ideal package for 3D imaging and 3D phenotypic characterization of more physiologically relevant cell culture models.

The Operetta is designed for fully-automated high-capacity, quantitative cellular analysis of fixed or live cells. It contains the highly sensitive sCMOS camera that provides a large field of view and high resolution image capture.

Operetta CLS is a high throughput microplate imager for high-content analysis (HCA). It can acquire, analyze and manage fluorescence, brightfield and digital phase contrast images. The combination of high power LED excitation with fast, precise mechanics and one large format sCMOS camera enables fast imaging.

Operetta® CLS™ is a high throughput microplate imager for high-content analysis (HCA). It can acquire, analyze and manage fluorescence, brightfield and digital phase contrast images. The combination of high power LED excitation with fast, precise mechanics and one large format sCMOS camera enables fast imaging.