Prodine [2] (trade names Prisilidine and Nisentil) is an opioid analgesic that is an analog of pethidine (meperidine). It was developed in Germany in the late 1940s. There are two isomers of the trans form of prodine, alphaprodine and betaprodine.
Prodine | C16H23NO2 | CID 6471 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Prodine (trade names Prisilidine and Nisentil) is an opioid analgesic that is an analog of pethidine (meperidine). It was developed in Germany in the late 1940s. Quick Facts Clinical data, ATC code ... There are two isomers of the trans form of prodine, alphaprodine and betaprodine.
Prodine (Prisilidine, Nisentil) is an opioid analgesic that is an analogue of pethidine (meperidine). There are two isomers of prodine, Alphaprodine and Betaprodine. [1] Betaprodine is some 5x more potent than alphaprodine, [2] but is metabolised more rapidly, and only alphaprodine was developed for medicinal use. It has similar activity to ...
Prodine, also known by the brand names Prisildine and Nisentil, is a synthetic opioid, analgesic drug used to provide pain relief, most commonly during labor and delivery, for minor surgical procedures, and in dentistry.
Desmethylprodine or 1-methyl-4-phenyl-4-propionoxypiperidine (MPPP, Ro 2-0718) is an opioid analgesic drug developed in the 1940s by researchers at Hoffmann-La Roche. [1] . Desmethylprodine has been labeled by the DEA as a Schedule I drug in the United States. It is an analog of pethidine (meperidine) a Schedule II drug.
It is a Opiates substance. An opioid analgesic chemically related to and with an action resembling that of MEPERIDINE, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
Synthesis of α- and β-Prodine according to US patent 2,765,315 Yield approx. 30% α-prodine + β-prodine From: Chemistry of Opioid Analgesics --PHY 422 - Neurology Pharmacotherapeutics Pharmacology Precursors 2-Phenyl-1-butene [2039-93-2], propionic acid, propionic anhydride and phosphoric acid are commercially available.
Prodine 5Mg Tablet is used in patients with akathisia and parkinsonism, and to reduce the adverse effects of anti-psychotic treatment for schizophrenic patients. Prodine 5Mg Tablet is also used to treat abnormal muscle contractions which result in twisting postures of the limbs or face.