Bacteriophage - Wikipedia
A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea. The term is derived from Ancient Greek φαγεῖν (phagein) 'to devour' and bacteria.
Bacteriophage-based advanced bacterial detection: Concept, …
2021年4月1日 · Phage-induced bacterial cell lysis and release of cytoplasmic contents, i.e., ATP, AK, progeny phage, and α-β-galactosidase enzymes. Each cytoplasmic content type is used as a sensing marker for bacterial detection.
Diverse phage communities are maintained stably on a clonal
2024年12月12日 · A key explanation for phage diversity is based on the diversity of their hosts. Each phage species tends to infect a narrow bacterial host range, so microbial communities with more bacterial diversity support more phage diversity ().Consistent with this, experiments show that communities with multiple bacterial species (), or even multiple bacterial strains of a single species (9, 10), can ...
Phages ensure their survival | Nature Reviews Microbiology
2019年7月15日 · Following induction of the lytic life cycle, phage DNA is packaged into virions and phage progeny is released by host cell lysis. Thus, phages are considered to be parasites that exploit...
Phage therapy: An alternative to antibiotics in the age of multi …
Genes for phage lytic enzymes are expressed by the bacterial host during the lytic cycle and assist the phage by hydrolyzing the cell wall to release viral progeny. The discovery and analysis of these proteins opens the possibility for the development of novel phage-based pharmaceuticals.
The language of phages | Nature Reviews Microbiology
2017年2月13日 · Phages exhibit two distinct life cycles in bacteria, a lytic cycle and a lysogenic cycle. During the lytic cycle, phages replicate and progeny particles are released through lysis. By...
Bacteriophage T4 Infection of Stationary Phase
Here, we show that bacteriophage T4 can efficiently bind to, infect and kill E. coli in stationary phase, both in the presence and absence of a functional stationary-phase sigma factor, and explore the response of T4-infected stationary phase cells to the addition of fresh nutrients 5 or 24 h after that infection.
A century of the phage: past, present and future
2015年11月9日 · In this Timeline, Salmond and Fineran discuss a century of phage research, describing the roles of phages in ecosystems and in driving bacterial evolution and virulence, and highlight their...
Contemporary Phage Biology: From Classic Models to New Insights
2018年3月8日 · At the end of the lytic infection cycle, progeny phage particles emerge from the cell in a process that usually involves cell lysis by phage proteins (Calendar and Abedon, 2006) (Figure 1 A). Most isolated phages (>95%) discovered to date have linear, double-stranded DNA (dsDNA) genomes packed into a tailed proteinaceous capsid ( Ackermann, 2007 ).
Bacteriophage - Biology LibreTexts
2023年6月20日 · Bacteriophage have been a powerful model genetic system, because they have small genomes, have a short life cycle, and produce many progeny from an infected cell. They provide a very efficient means for transfer of DNA into or between cells. The large number of progeny makes it possible to measure very rare recombination events.