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  1. Scleroderma - Symptoms and causes - Mayo Clinic

    • Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. It may also cause problems in the blood vessels, internal organs a… 展开

    Symptoms

    Skin-related signs and symptoms
    Nearly everyone who has scleroderma experiences a … 展开

    Mayo Clinic
    Causes

    Scleroderma results from an overproduction and accumulation of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body's connectiv… 展开

    Mayo Clinic
    Risk factors

    Anyone can get scleroderma, but it does occur much more often in women than in men. Several combined factors appear to influence the risk of developing scleroderma:… 展开

    Mayo Clinic
    Complications

    Scleroderma complications range from mild to severe and can affect the:
    •Fingertips. In systemic sclerosis, Raynaud's phenomenon can become so severe that the r… 展开

    Mayo Clinic
     
  1. Autoimmune disease
    • 根据 2 个来源
    Scleroderma is believed to be an autoimmune disease. This means that it occurs in part because the body's immune system begins to attack the connective tissues.
    Scleroderma literally means hard skin. Scleroderma is classified as an autoimmune disease. This means that a person’s immune system works against itself.
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  3. Scleroderma: Symptoms, Causes & Treatment Options

    It’s an autoimmune condition, which means your immune system attacks your body instead of protecting it. Scleroderma can cause lots of symptoms and affect tissue throughout your body. It can also lead to life-threatening complications.

  4. What Is Scleroderma? Symptoms & Causes| NIAMS

    2023年6月22日 · Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it …

  5. Scleroderma: Causes, Symptoms, and Treatment - WebMD

  6. Scleroderma - Wikipedia

  7. What is Scleroderma? : Johns Hopkins Scleroderma …

    Scleroderma is a chronic condition that causes hardening of connective tissue in the body. Learn about the symptoms, types, causes, and treatments of this rare and complex disease from Johns Hopkins experts.

  8. Systemic Sclerosis (Scleroderma): Pictures, Symptoms, …

    2023年2月8日 · Systemic sclerosis (scleroderma) is an autoimmune disorder that causes connective tissue to thicken and stiffen. It can affect your skin, blood vessels, muscles, heart, lungs, kidneys, and digestive system. Learn about …

  9. Scleroderma > Fact Sheets - Yale Medicine

    Scleroderma is an autoimmune disease in which the body produces too much collagen, a fibrous protein that is a major component of the body’s connective tissues, including the skin, muscles, bones, tendons, and cartilage. It is also …

  10. Scleroderma Basics: Overview, Symptoms, and Causes

    2023年6月22日 · What is scleroderma? Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types …

  11. Understanding Scleroderma | HSS Scleroderma Center

    2023年6月27日 · What is scleroderma? Scleroderma is an autoimmune condition that can lead to a tightening or hardening of the skin and, in some cases, internal organs. It is a chronic condition in which the immune system mistakenly …