Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease affects more than 100,000 people in the United States and 8 million people worldwide. In the United States, 9 of 10 people who have sickle cell disease are of African ancestry or identify as Black: About 1 in 13 Black babies are born with sickle cell trait, meaning that they inherited a sickle cell gene from one parent.
Sickle Cell Disease - Symptoms | NHLBI, NIH
2024年8月20日 · Serious symptoms of sickle cell disease are emergencies and need treatment right away. Seek care or call 9-1-1 if you or someone else is experiencing: Severe pain. A serious pain event is sometimes called a “pain crisis,” “sickle cell crisis,” or “vaso-occlusive crisis.” Most people with sickle cell disease have this often-serious pain.
Sickle Cell Disease - Diagnosis | NHLBI, NIH
2024年9月9日 · Similar tests can also look for other abnormal hemoglobin types. Genetic tests can help confirm a sickle cell disease diagnosis if results from blood tests are not clear. Some people who have sickle cell disease have one gene for sickle hemoglobin and another gene for a different type of faulty hemoglobin that causes diseases such as ...
Sickle Cell Disease Fact Sheet - NHLBI, NIH
Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD. Print Length:
Sickle Cell Disease - Causes and Risk Factors - NHLBI, NIH
2024年8月20日 · This child has sickle cell trait and is a carrier of the hemoglobin S gene. A 25%, or 1 in 4, chance of inheriting two hemoglobin S genes. This child has sickle cell disease. It is important to keep in mind that each time this couple has a child, the chances of that child having sickle cell disease remain the same.
Sickle Cell Disease - Sickle Cell Trait - NHLBI, NIH
2024年8月22日 · Sickle cell trait does not turn into sickle cell disease. In contrast, people with sickle cell disease have two copies of the hemoglobin S gene. Some people have sickle cell disease because they have one hemoglobin S gene and another gene for a different faulty hemoglobin. Without a gene to produce normal hemoglobin A, red blood cells break ...
How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
2024年8月22日 · Some ulcers return even after healing. People who have sickle cell disease usually do not get ulcers until after age 10. Liver problems: Sickle cell intrahepatic cholestasis is an uncommon but serious type of liver damage that happens when sickled red cells block blood vessels in the liver. This blockage prevents enough oxygen from reaching ...
Sickle Cell Disease - Treatment | NHLBI, NIH
2024年9月30日 · Hydroxyurea is an oral medicine that is frequently prescribed to help treat sickle cell disease. Hydroxyurea is an oral medicine that can reduce sickling of red blood cells and help prevent serious symptoms of sickle cell disease, including pain crises. Healthcare providers usually prescribe daily hydroxyurea for infants as young as 9 months ...
Your Guide to Anemia | NHLBI, NIH
This booklet provides an overview of anemia for health consumers, covering causes, risk factors, diagnosis, and treatment. Also addresses major types of anemia: iron-deficiency, pernicious, aplastic, and hemolytic. Contains section on healthy lifestyle, working with your doctor, and talking with your family.
Shedding light on a neglected form of sickle cell disease
2024年9月25日 · The research is led by NHLBI grantee Julie Kanter, M.D., a professor at the University of Alabama at Birmingham and director of the school’s Adult Sickle Cell Program. Conducted as part of the NHLBI-funded Sickle Cell Disease Implementation Consortium (SCDIC), the study included 2,282 individuals ages 15 - 45 years, with sickle cell disease ...