Single-domain antibody - Wikipedia
A single-domain antibody (sdAb), also known as a Nanobody, is an antibody fragment consisting of a single monomeric variable antibody domain. Like a whole antibody, it is able to bind …
Structure and development of single domain antibodies as …
Here, we review the structural and biophysical properties of VHH domains, highlight recent VHH-based therapeutics and diagnostics, and provide insight into VHH engineering that may pave …
Single-Domain Antibodies as Antibody–Drug Conjugates: From …
Single-domain antibodies offer unique advantages, including small size, high stability, specificity, ease of production, and low immunogenicity, positioning them as a promising tool for future …
Single domain antibody: Development and application in
2024年8月21日 · Heavy-chain antibodies (HCAbs) are a unique type of antibodies devoid of light chains, and comprised of two heavy chains-only that recognize their cognate antigen by virtue …
Single-Domain Antibody - an overview | ScienceDirect Topics
Single-domain antibodies (sdabs) existence in camelid species and cartilaginous fishes, are the antigen-binding moiety of heavy chain antibodies with small size, high production yield and …
Camelid Single-Domain Antibodies: Historical Perspective and …
In this article, I present a historical perspective on the development of camelid single-domain antibodies (sdAbs or V H Hs, also widely known as nanobodies) since their discovery and …
Single-Domain Antibodies or Nanobodies: A Class of Next
Single-domain antibodies or nanobodies are a class of next-generation antibodies that have specific features: small size (in nanoscale), high penetration in various tissues, high stability in …
Single Domain Antibody Database
We have established the first dedicated single domain antibody repository and database. The database hosts a large collection of natural and synthetic camelid single domain antibody …
Single-Domain Antibodies: Methods and Protocols - Springer
This volume covers current and emerging techniques for studying single-domain antibodies (sdAbs). Chapters guide readers through the biology and immunology of sdAbs in camelids …
Single-Domain Antibody - an overview | ScienceDirect Topics
A single-domain antibody (sdAb) is a type of antibody that consists of only one variable domain of the heavy chain and does not have a light chain. Despite its small size, sdAb has the ability to …